经导管肝动脉化疗栓塞治疗结直肠癌肝转移瘤

目的　总结经导管肝动脉化疗栓塞治疗结直肠癌肝转移瘤的效果。方法　 42例结直肠癌肝转移者 ,其中单纯灌注化疗 14例 ,化疗栓塞 2 8例。经肝动脉灌注化疗药物 ,碘油药物乳剂和明胶海绵栓塞。结果　完全缓解 (CR) 2例 (4 .8% ) ,部分缓解 (PR) 2 0例 (4 7.6 % ) ,无变化 (NC) 18例(4 2 .9% ) ,进展 (PD) 2例 (4 .8% ) ,有效率 (CR PR) 5 2 .4% (2 2 / 42 )。平均生存期为 16 .4个月。 0 .5、1和 2年的生存率分别为 90 .5 %、6 6 .7%和 2 3.8%。结论　经导管肝动脉化疗栓塞治疗结直肠癌肝转移是一种有效的方法

Transcatheter hepatic artery chemo-embolization for liver metastasis from colorectal carcinomas

Objective To analyse the clinical effectiveness of transcatheter hepatic artery chemo embolization on hepatic metastasis from colorectal carcinomas.Methods 42 cases were divided into 2 groups:simple chemotherapy group ( n =14), chemotherapy and embolization group ( n =28). After catheter was selectively inserted into hepatic artery, and then followed by chemotherapy, lipiodol and gelfoam infusion. Results CR 2 cases (4.8%); PR 20 cases (47.6%); NC 18 cases (42.9%); PD 2 cases (4.8%). The total anticancer effective rate (CR PR) was 52.4%. The avevage survival time was 16.4 months. The 0.5 ,1 ,2 year survival rates were 90.5%, 66.7% and 23.8%, respectively.Conclusions Transcatheter hepatic artery chemo embolization is an effective method to treat liver metastasis of colorectal carcinomas. It is more effective than the simple chemotherapy.