Large volume N2O uptake alone does not explain the second gas effect of N2O on sevoflurane during constant inspired ventilation期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Large volume N2O uptake alone does not explain the second gas effect of N2O on sevoflurane during constant inspired ventilation

Authors:	Hendrickx J F A Carette R Lemmens H J M De Wolf A M

Affiliation:	¹ Department of Anesthesia, Stanford University School of Medicine, Stanford, CA, USA. ² Department of Anesthesiology, Intensive Care and Pain Therapy, Onze Lieve Vrouwziekenhuis, Aalst, Belgium. ³ Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

Abstract:	Background. The second gas effect (SGE) is considered to besignificant only during periods of large volume N₂O uptake (VN₂O);however, the SGE of small VN₂O has not been studied. We hypothesizedthat the SGE of N₂O on sevoflurane would become less pronouncedwhen sevoflurane administration is started 60 min after thestart of N₂O administration when VN₂O has decreased to

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