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Surgery for temporal lobe epilepsy after cerebral malaria
Authors:O.E.M.G. Schijns   V. Visser-Vandewalle   E.M.P. Lemmens   A. Janssen  G. Hoogland
Affiliation:aDepartment of Neurosurgery, University Hospital Maastricht, Maastricht, The Netherlands;bDepartment of Psychiatry and Neuropsychology, Division Cellular Neuroscience, Maastricht University, Maastricht, The Netherlands;cDepartment of Epileptology, Epilepsy Centre Kempenhaeghe, Heeze, The Netherlands
Abstract:
The most common indication for epilepsy surgery is temporal lobe epilepsy (TLE) which usually is divided into two categories, mesial and lateral TLE. The commonest pathology underlying mesial temporal lobe epilepsy (MTLE) is mesial temporal sclerosis (MTS); we report on a 50-year-old male patient, who contracted cerebral malaria and developed MTLE shortly thereafter. Magnetic resonance imaging (MRI) showed MTS. Surgical treatment was an anteromedial temporal lobe resection with amygdalohippocampectomy. The patient is seizure free, 36 months after surgical treatment. This is the first report describing MTLE-onset subsequent to cerebral malaria and discussing the potential pathophysiological relationship between cerebral malaria and MTS.
Keywords:Cerebral malaria   Temporal lobe epilepsy   Mesial temporal sclerosis   Epilepsy surgery
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