Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo |
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| Authors: | Rhee Yumie Bivi Nicoletta Farrow Emily Lezcano Virginia Plotkin Lilian I White Kenneth E Bellido Teresita |
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| Affiliation: | aDepartment of Anatomy and Cell Biology, Indiana University School of Medicine, USA;bDepartment of Medicine, Division of Endocrinology, Indiana University School of Medicine, USA;cDepartment of Molecular Genetics, Indiana University School of Medicine, USA |
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| Abstract: | |
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| Keywords: | Abbreviations: PTH, parathyroid hormone DMP1-caPTHR1, dentin matrix protein 1-constitutively active PTH receptor 1 mice FGF23, fibroblast growth factor 23 PTHrP, PTH related protein FGFR1, FGF receptor 1 GALNT3, galactosaminyl transferase 3 BMP, bone morphogenetic protein Pi, inorganic phosphate NPT2A, sodium-phosphate co-transporter 1,25-D3, 1,25-dihydroxy-vitamin D3 CKD, chronic kidney disease GFP, green fluorescent protein DBA, dibutyrylcyclic AMP MEM, minimal essential medium SD, standard deviation ANOVA, analysis of variance WT, wild type ERKs, extracellular signal regulated kinases |
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