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| MAC/顺铂方案治疗恶性滋养细胞肿瘤 | |
| 引用本文： | 杨国奋,易村健,梅卓贤,何勉. MAC/顺铂方案治疗恶性滋养细胞肿瘤[J]. 中国癌症杂志, 2000, 10(1): 69-70 |
| 作者姓名： | 杨国奋 易村健 梅卓贤 何勉 |
| 作者单位： | 1. 中山医科大学附属第一医院妇产科,广东,广州,510080 2. 湖北沙市第一人民医院妇产科,湖北,沙市,434000 |
| 摘 要： | 目的：研究ＭＣＡ「甲氨蝶呤、放线菌素Ｄ（更生霉素）、环铂（ＤＤＰ）方案治疗恶性滋养细胞肿瘤的疗效。方法：回顾性分析中山医科大学附属第一医院１９８６年１月－１９９５年１月间以ＭＡＣ／ＤＤＰ方案治疗６２例恶性滋养细胞肿瘤患者的疗效、副反应及随记结果。结果：绒癌的治愈率达８５．２９％，侵蚀性葡萄胎１００％；死亡５例，均为晚期绒癌；中度毒副反应７例；轻度反应５５例；患者经３－６年随访，２例复发，再以ＭＡＣ |
| 关 键 词： | 滋养细胞肿瘤 甲氨蝶呤 MAC 顺铂 |
| 文章编号： | 1007-3639(2000)01-0069-02 |
| 修稿时间： | 1999-02-02 |
Treatment of malignant trophoblastic tumor by MAC/cisplatin |
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| YANG Guo feng,YI Chun jiang,MEI Zhuo xian,et al.. Treatment of malignant trophoblastic tumor by MAC/cisplatin[J]. China Oncology, 2000, 10(1): 69-70 | |
| Authors: | YANG Guo feng YI Chun jiang MEI Zhuo xian et al. |
| Abstract: | Purpose:To study the effectiveness of MAC/cisplatin(DDP)on patients with malignant trophoblastic tumor.Methods:The chart and follow up data of 62 patients treated from 1986 to 1995 in the First Affiliated Hospital of Sun Yat sen University of Medical Sciences were reviewed.These patients were treated by MAC/DDP.The treatment results, side effects and follow ups were retrospectively analysed. Results:The cure rates of choriocarcinoma and invasion mole were 85.29% and 100%. Five patients died of advanced choriocarcinoma. Seven cases had moderate side effects and 55 cases had light side effects. All patients were followed up from 3 to 5 years. Conclusions:The clinical cure rate of MAC/DDP is high and its side effects is light. It can be used for the high risk,drug resistant and recurring type of malignant trophoblastic tumor. |
| Keywords: | trophoblastic methotrexate cisplatin chemotherapy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |