丙泊酚复合七氟烷对小儿麻醉苏醒期躁动的疗效分析

目的研究丙泊酚复合七氟烷对小儿麻醉苏醒期躁动的临床疗效。方法选择2009年3月至2011年3月在东莞市仁康医院诊治的常规手术麻醉患儿150例,按照随机数字表法分为试验组和对照组各75例。对照组患儿采用七氟烷进行吸入麻醉,试验组患儿采用丙泊酚复合七氟烷进行麻醉。记录两组患儿麻醉苏醒期躁动情况和清醒时间,并加以分析。结果试验组患儿的躁动发生率显著低于对照组(16%vs 53.3%)(χ2=1.085,P<0.05),且平均躁动时间显著低于对照组(t=0.040,P<0.05);试验组患儿清醒时间显著长于对照组(t=3.054,P<0.05);试验组躁动时间>15 min患儿所占比例显著少于对照组(10.7%vs 49.3%)(χ2=2.14,P<0.05)。结论丙泊酚复合七氟烷可显著减少小儿麻醉苏醒期的躁动,疗效明显优于单纯七氟烷。

The Efficacy Analysis of Propofol Sevoflurane Anesthesia in Children Waking Period Restlessness

Objective To study the clinical efficacy of propofol combining sevoflurane anesthesia in the treatment of children waking restlessness.Methods One hundred and fifty patients in Renkang Hospital of Dongguan from March 2009 to March 2011 were studied.In accordance with the law of the random number table,patients were randomly divided into two groups of trial and control groups,75 patients in each group.The control group were treated with sevoflurane inhalation anesthesia;the trial group were treated with propofol combined with sevoflurane anesthesia.The children anesthesia restlessness and awake time were recorded and compared.Results The restlessness incidence(16%) of the trial group was significantly lower than the control group(53.3%),with significant difference(χ2 = 1.085,P < 0.05);the average agitation time of the trial group was significantly shorter than the control group(t = 0.040,P < 0.05).Patients awake time of the trial group was significantly longer than the control group(t = 3.054,P < 0.05);The experimental group restlessness > 15 min children proportion(10.7%) was significantly less than that of the control group(49.3%),with significant difference(χ2 = 2.14,P < 0.05).Conclusion Propofol combined with sevoflurane can significantly reduce pediatric anesthesia waking agitation,with much better effect than the simple use of sevoflurane.