The T4 molecule: function and structure |
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| Affiliation: | 1. Cellular and Molecular Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran;2. Clinical Immunology Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran;3. Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran;4. Department of Biology, Zabol University, Zabol, Iran;5. Department of Clinical Biochemistry and Molecular Biology, School of Medicine, Shahidsadoughi University of Medical Sciences, Yazd, Iran;6. Department of laboratory sciences, School of Allied Medicine, Zahedan University of Medical Sciences, Zahedan, Iran |
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| Abstract: | ![]()
T4 antigen bearing T lymphocytes are central immunoregulatory cells which display helperlinducer functions, proliferate in response to antigen, control suppression and release lymphokines. In this review, Angus Dalgleish describes growing evidence that these different functions are carried out by phenotypically different subpopulations of T4-positive T cells, and discusses T4 as a putative receptor for class II MHC molecules and HTLV-III. |
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