牙周炎患者的血脂、血糖水平分析

目的分析牙周炎对患者血糖和血脂水平的影响。方法对117例侵袭性牙周炎(AgP)患者、40例慢性牙周炎(CP)患者及37名牙周健康者,空腹抽取静脉血,检测血脂、血糖水平,比较3组之间的差异。结果AgP患者平均甘油三酯水平[(1．09±0．79)mmol／L]显著高于健康对照者[(0．94±0．28)mmol／L,P<0．05];CP和AgP患者的血糖水平[分别为(5．40±1．01)mmol／L和(5．07±0．66)mmoL／L]均高于健康对照者(4．62±0．64 mmol／L),P< 0．01;CP组的总胆固醇高于健康对照组,P<0．05;AgP组的重度位点百分比与总胆固醇呈正相关(r=0．25,P<0．01)。结论牙周炎可能会影响血糖和血脂的水平。

Blood lipids and glucose levels in patients with periodontitis

OBJECTIVE: To determine the serum levels of lipid and glucose in patients with periodontitis. METHODS: The patients with aggressive periodontitis (AgP, n = 117) and chronic periodontitis (CP, n = 40) and healthy controls (n = 37) were recruited. Peripheral blood sample was obtained from each subject by venipuncture. Serum chemistry variables including total cholesterol, triglycerides, and fasting glucose were analyzed by biochemical analyzer. RESULTS: The average serum levels of triglycerides and glucose of the patients with AgP [(1.09 +/- 0.79) mmol/L and (5.07 +/- 0.66) mmol/L] were both significantly higher than those of the control group [(0.94 +/- 0.28) mmol/L and (4.62 +/- 0.64) mmol/L], P < 0.05. Higher serum levels of total cholesterol and glucose were also observed in patients with CP [(4.61 +/- 1.23) mmol/L and (5.40 +/- 1.01) mmol/L] compared with controls [(4.49 +/- 0.78) mmol/L and (4.62 +/- 0.64) mmol/L], P < 0.05. Serum level of total cholesterol in AgP group was positively associated with percentage of severe sites (r = 0.25, P < 0.01). CONCLUSIONS: Patients with periodontitis may have altered serum lipid and glucose levels compared with controls.