长江流域6城市233家医院2007-2009年质子泵抑制剂利用分析

目的:评价长江流域医院质子泵抑制剂(PPI)的应用现状及趋势。方法:采用回顾性方法,对长江流域6城市233家医院2007-2009年PPI的销售金额和用药频度(DDDs)等进行统计、分析。结果:该地区医院PPI的总销售金额及总DDDs呈逐年增长趋势。其中,奥美拉唑的总销售金额及DDDs居第1位,雷贝拉唑的DDDs由2007年的第5位上升至2009年的第3位;新上市的艾普拉唑的用量增长迅速。该地区医院的PPI销售金额排序稳定,上海地区销售金额占总销售金额的40%以上,稳居第1位。口服PPI的DDDs比例达70%以上,应用较多;但注射剂的销售金额构成比及DDDs构成比均逐年增加,应用增长较快。结论:长江流域6城市233家医院的PPI应用广泛,总体呈上升趋势,并将进一步持续增长。

Analysis of the Utilization of Proton Pump Inhibitors in 233 Hospitals from 6 Cities of the Yangtze Valley during the Period of 2007-2009

OBJECTIVE：To evaluate the status quo and tendency of the utilization of proton pump inhibitors （PPI） in the Yangtze valley. METHODS：By retrospective method, the utilization of PPI in 233 hospitals from 6 cities of Yangtze valley during the period of 2007-2009 was analyzed statistically in respect of consumption sum and DDDs. RESULTS：The total consumption sum and the DDDs of PPI were increasing year by year. Omeprazole took up the first place of total consumption sum and DDDs among PPI. Rabeprazole ended up at third place in 2009 in the list of DDDs, from fifth place in 2007. The consumption of ilaprazole had been growing rapidly. The order of consumption sum of PPI was basically stable in these regions, and Shanghai occupied more than 40% of the total consumption sum, remaining its leading position. DDDs of oral PPI shared 70% or more, while the constituent ratio of consumption sum and DDDs of injection were increasing rapidly year by year. CONCLUSION： PPI are widely used in 233 hospitals from 6 cities of the Yangtze valley. Application of PPI shows an upward trend on the whole and will have further development.