青霉素左氧氟沙星致意识障碍一例

1例19岁女性患者因"急性扁桃体炎"给予青霉素320万U溶于0.9%氯化钠100mL中静脉滴注,每天2次。次日患者诉头晕,家人发现患者思睡,很容易叫醒。改为左氧氟沙星0.4g静脉滴注,每天1次,使用3d。用药次日,发现患者睡眠明显增多,大声呼喊方可唤醒,不主动进食,不主动讲话,记忆力明显下降,有时不认识家人。停用3d后症状减轻,2周后恢复正常。本文对该病例进行分析、总结。

Consciousness impairment induced by penicillin and levofloxacin

A 19-year-old woman received an IV infusion of penicillin 3,200,000 U dissolved in 100 mL of sodium chloride 0.9% twice a day for an acute tonsillitis.Next day the patient felt dizziness and was found drowsy and could be called awake easily.Replaced with levofloxacin 0.4 g once a day for 3 days.Next day her family found the patient's sleeping markedly increased and might be waked up by loudly loud and could not take food and speak on one's own.The patient's memory decreased obviously.Sometimes she could not distinguish her family households.Levofloxacin was stopped.Her systems alleviated 3 days later and got right 2 weeks later.