危重病患者静注胺碘酮的疗效及安全性

目的 :评价急危重疾病合并心律失常患者静注胺碘酮的疗效及安全性。方法 :选择急诊危重症合并快速心律失常患者 6 8例 ,其中 4 9例伴不同程度的心力衰竭。患者均接受静注胺碘酮治疗 ,根据心律失常转复为窦性心律或心率减慢、期前收缩减少或心律失常未纠正、心率未减慢而分别评为显效、有效和无效。同时分析用药前后的血压、心率以及药物不良反应 ,并评价心力衰竭有无加重。结果 :6 8例患者中显效率 6 7.7% ,有效率4 5 .6 % ,无效率 7.4 % ,无心力衰竭加重 ,无严重的药物不良反应发生。结论 :危重症合并快速心律失常特别是缺血性心脏病合并心功能不全患者 ,静注胺碘酮是有效和安全的。

Efficacy and safety of intravenous amiodarone in critically ill

Objective:To investigate efficacy and safety of intravenous amiodarone in critically ill with arrhythmia. Methods:Sixtyeight consecutive patients with tachycardia arrhythmia received intravenous amiodarone were included in this study.Of 68,49 patients had vary degree heart failure,1 patient with serious low blood pressure.Blood pressure and heart rate before and after intravenous amiodarone were compared, effects and side effects of intravenous amiodarone were analyzed.Results:Clearly effect,effect and no avail rates respectively were 67 7%,45 6% and 7 4%.Heart failure did not deteriorate.No serious side effect was observed during intravenous amiodarone.Conclusions:It is efficacy and safety of intravenous amiodarone in critically ill in the patients presenting to the emergency room,especially for whose with heart failure.