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中药注射剂不良反应文献分析
引用本文:马鸿雁,辛征骏,孙翠萍,李霞,张海燕,杨明.中药注射剂不良反应文献分析[J].药物流行病学杂志,2010(7):420-423.
作者姓名:马鸿雁  辛征骏  孙翠萍  李霞  张海燕  杨明
作者单位:[1]成都中医药大学,成都610075 [2]现代中药制剂教育部重点实验室,成都610075
基金项目:基金项目:中医药行业科研专项项目(编号:200708006)
摘    要:目的:通过中药注射剂不良反应文献分析,系统了解既往中药注射剂不良反应发生情况,为临床安全、合理使用中药注射剂提供参考。方法:以1989~2008年68种中药注射剂不良反应报道的文献为调查对象,进行综合分析。结果:共查得文献1687篇,不良反应表现以过敏反应、心血管系统、呼吸系统为多;刺五加注射液、双黄连注射液、清开灵注射液不良反应较多。结论:中药注射剂的不良反应与性别、年龄、体质有关;具有普遍性、多样性、快速性等特征。

关 键 词:中药注射剂  药物不良反应  安全用药

Analysis of Literatures of Adverse Reactions of Traditional Chinese Medicine Injections
Ma Hongyan,Xin Zhengjun,Sun Cuiping,Li Xia,Zhang Haiyan,Yang Ming.Analysis of Literatures of Adverse Reactions of Traditional Chinese Medicine Injections[J].Chinese Journal of Pharmacoepidemiology,2010(7):420-423.
Authors:Ma Hongyan  Xin Zhengjun  Sun Cuiping  Li Xia  Zhang Haiyan  Yang Ming
Institution:1. Chengdu University of TCM, Chengdu 610074, China ;2. Key Laboratory of Modem Preparations of Traditional Chinese Medicine)
Abstract:Objective:To investigate the occurrence of adverse reactions of Traditional Chinese Medicine preparations to guide the safety administration and application. Method :The literatures about 68 kinds of TCM injections were collected between 1989 and 2008. Result:In the 1687 pieces of literatures obtained, adverse injection reactions occurred more in anaphylaetic responses, cardiovascular system, and respiratory system. There were many adverse reactions in the injections of ciwujia, shuanghuanglian and qingkailin. Conclusion:The adverse reactions of TCM injections were related to sex, age and corporeity and characterized by their catholicity, diversity and suddenness.
Keywords:TCM injections  Adverse drug reactions  Review
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