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代谢综合征患者的心率变异性及其影响因素
引用本文:郝钰,杨锐英. 代谢综合征患者的心率变异性及其影响因素[J]. 现代保健, 2012, 0(11): 12-14
作者姓名:郝钰  杨锐英
作者单位:[1]宁夏医科大学临床医学院,宁夏银川750004 [2]宁夏医科大学总医院,宁夏银川750004
摘    要:
目的:探讨代谢综合征患者心率变异性(HRV)的特点以及影响HRV的因素。方法:选择明确诊断为代谢综合征(MS)的患者45例,同时选择33例健康对照者。所有被研究者均行24h动态心电图监测,以获得HRV各项时域指标,通过对比分析以明确两组间HRV差异;采用多元线性回归法分析影响HRV的因素。结果:代谢综合征组HRV各项时域指标明显下降(P〈0.05),且血压、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FBG)、腰围(WC)均为HRV的影响因素。结论:(1)代谢综合征患者存在自主神经功能紊乱,表现为交感及迷走神经均受损;(2)血压、TG、FBG、WC、HDL-C均为HRV降低的危险因素。

关 键 词:代谢综合征  心率变异性  自主神经功能紊乱

Heart Rate Variability in Patiens with Metabolic Syndrome and its Influence Factor
HAO Yu,YANG Rui-ying. Heart Rate Variability in Patiens with Metabolic Syndrome and its Influence Factor[J]. , 2012, 0(11): 12-14
Authors:HAO Yu  YANG Rui-ying
Affiliation:.(Ningxia Medical University,Yinchuan 750004,China )
Abstract:
Objective:To research the characteristic of heart rate variability(HRV) in patients with metabolic syndrome(MS) and discuss the influence factors about the HRV.Methods:45 patients suffering from MS and 33 normal subjects were examined by the use of HOLTER in order to acquire the time domain indexes consequently and make clear the difference.The linear multivariate regression analysis was performed to select variable associated with HRV from the following:age,sex,waistline,smoking,blood pressure,TG,HDL-C,FBG,BMI.Results:Compared with the healthy group,each time domain index was declined obviously(P0.05) in MS group.The linear multivariate regression analysis showed that waistline,blood pressure,TG,HDL-C,FBG was associated with HRV.Conclusion:(1)There was dysfunction of the autonomic nervous system in patients with MS,performance for the sympathetic nerve and vagus nerve are both damaged;(2)Blood pressure,TG,FBG,WC,HDL-C are all the risk factors about HRV reduction.
Keywords:Metabolic syndrome  Heart rate variability  Autonomic nervous system
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