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急性有机磷农药中毒胆碱酯酶活性变化与反跳的关系
引用本文:刘云建 侯云修. 急性有机磷农药中毒胆碱酯酶活性变化与反跳的关系[J]. 滨州医学院学报, 1996, 19(2): 122-123
作者姓名:刘云建 侯云修
作者单位:Emergency Department,Affiliated Hospital,Binzhou Medical College,Binzhas 256603
摘    要:
应用酶动力学法动态测定45例中,重度急性有机磷农药中毒者血清胆碱酯酶活性的变化,发现所有患者于中毒第2天胆碱酯酶活性升高,第3天迅速降低,在此低水平数天丙逐渐恢复到正常水平。中毒反跳发生的时间均在胆碱酯酶活性下降的时期内。

关 键 词:有机磷 农药中毒 胆碱酯酶活性 中毒反跳

RELATIONSHIP BETWEEN THE CHANGES OF CHOLINESTERASE ACTIVITY OF ACUTE ORGANOPHOSPHORUS INSECTISIDES POISONING AND POISONING RESBOUND
Liu Yunjian, et al. RELATIONSHIP BETWEEN THE CHANGES OF CHOLINESTERASE ACTIVITY OF ACUTE ORGANOPHOSPHORUS INSECTISIDES POISONING AND POISONING RESBOUND[J]. Journal of Binzhou Medical College, 1996, 19(2): 122-123
Authors:Liu Yunjian   et al
Abstract:
The changes of cholinesterase activity in 45 cases of moderate and severe acute organophosphorus insectisides poisoning were studiel by using enzyme kinetics method. It was found that cholinesterase activity increased significantly on day 2(P<0. 05), rapidly decreased statistically on day 3(P<0.05),and at the low level continued for several days,then increased to normal level gradually . The poisoning rebound time of all cases occurred in the decrease period of cholinesterase activity. The result indicates that according to the changes of cholinesterase activity, it is important to use anticholinergic drugs and cholinesterase reactivators correctly for preventing poisoning rebound.
Keywords:organophosphorus insectisides poisoning  cholinesterase  change  poisoning rebound  
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