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芪蛭汤对肾病综合征患者血浆内皮素、一氧化氮及24h尿蛋白定量水平的影响
引用本文:刘洪,杨敬,熊维建,李荣亨. 芪蛭汤对肾病综合征患者血浆内皮素、一氧化氮及24h尿蛋白定量水平的影响[J]. 中国中医急症, 2011, 20(12): 1905-1907
作者姓名:刘洪  杨敬  熊维建  李荣亨
作者单位:1. 重庆市中医院,重庆,400021
2. 重庆医科大学附属第一医院,重庆,400010
基金项目:重庆市卫生局中医药科技项目
摘    要:
目的探讨芪蛭汤治疗肾病综合征的机理。方法将肾病综合征患者75例随机分为两组,均给予对症治疗和泼尼松加环磷酰胺治疗;治疗组加予芪蛭汤随证加味;对照组加予阿魏酸哌嗪片口服,1个月后观察两组临床疗效及治疗前后血浆内皮素、一氧化氮浓度、24h尿蛋白定量。结果治疗组疗效优于对照组。治疗后两组血浆内皮素、24h尿蛋白定量均降低,血浆一氧化氮水平均增高;治疗组改善均优于对照组。结论芪蛭汤能降低肾病综合征患者内皮素/一氧化氮比值,保护血管内皮细胞,降低蛋白尿。

关 键 词:肾病综合征  芪蛭汤  24h尿蛋白定量  内皮素  一氧化氮

Effect of Qizhi Decoction on ET, NO and 24h Urine Protein in Nephrotic Syndrome
LIU Hong,YANG Jing,XIONG Wei-jian,et al.. Effect of Qizhi Decoction on ET, NO and 24h Urine Protein in Nephrotic Syndrome[J]. Journal of Emergency in Traditional Chinese Medicine, 2011, 20(12): 1905-1907
Authors:LIU Hong  YANG Jing  XIONG Wei-jian  et al.
Affiliation:LIU Hong,YANG Jing,XIONG Wei-jian,et al. TCM Hospital of Chongqing City(Chongqing 400021)
Abstract:
Objective: To investigate the mechanism of Qizhi Decoction on the nephritic syndrome.Methods: 75 nephritic syndrome patients were randomly divided into the treatment group and the control group.The symptomatic treatment and the prednisone plus cyclophosphamide were used in two groups.The Qizhi Decoction was given in the treatment group and the piperazine was taken in the control group.After 1 month,some indices were observed before and after therapy including the serum endothelin,the nitric oxide,the 24h ur...
Keywords:Nephritic syndrome  Qizhi Decoction  24h urine protein  Endothelin  Nitric oxide  
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