| 肿瘤抑制因子PTEN蛋白在成年大鼠中枢神经系统的表达 |
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| 引用本文： | 蔡其燕,姚忠祥. 肿瘤抑制因子PTEN蛋白在成年大鼠中枢神经系统的表达[J]. 第三军医大学学报, 2007, 29(5): 384-386 |
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| 作者姓名： | 蔡其燕 姚忠祥 |
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| 作者单位： | 第三军医大学基础医学部组织学与胚胎学教研室,重庆市神经科学研究所,重庆,400038;第三军医大学基础医学部组织学与胚胎学教研室,重庆市神经科学研究所,重庆,400038 |
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| 摘 要： | 目的 观察PTEN在成年大鼠中枢神经系统(central nervous system, CNS)的表达情况.方法 用免疫组织化学ABC法显示大鼠CNS中PTEN阳性免疫反应产物.结果 PTEN阳性反应产物广泛分布于大鼠的CNS内,阳性细胞的分布主要表现为较多、中等量和少量3种情况,其亚细胞定位包括细胞质、细胞核和细胞质突起.结论 明确PTEN在成年大鼠CNS中的表达模式.
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| 关 键 词： | PTEN 中枢神经系统 表达 |
| 文章编号： | 1000-5404（2007）05-0384-03 |
| 修稿时间： | 2006-06-26 |
Expression of tumor suppressor PTEN protein in central nervous system of adult rats |
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| CAI Qi-yan,YAO Zhong-xiang. Expression of tumor suppressor PTEN protein in central nervous system of adult rats[J]. Acta Academiae Medicinae Militaris Tertiae, 2007, 29(5): 384-386 |
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| Authors: | CAI Qi-yan YAO Zhong-xiang |
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| Affiliation: | Department of Histology and Embryology, College of Medicine, Third Military Medical University, Chongqing 400038, China |
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| Abstract: | Objective To investigate the expression characteristics of the phosphatase and tensin homolog deleted on the chromosome 10 (PTEN) in the central nervous system(CNS) of adult rats. Methods Immunohistochemical staining was used to demonstrate the PTEN-like positive immunohistochemical product. Results Expression of PTEN was extensive in the CNS. The distribution of positive cells was strong, moderate or weak and its subcellular localization included the cytoplasm, nuclei and processes. Conclusion The present results identify the expression of PTEN protein in the CNS of adult rats. |
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| Keywords: | PTEN |
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