| 复发性外阴阴道念珠菌病患者阴道分泌物IL-4和IL-12的检测 |
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| 引用本文： | 高飞,曹萍,董跃兰,杜鹏,吴颖.复发性外阴阴道念珠菌病患者阴道分泌物IL-4和IL-12的检测[J].中国皮肤性病学杂志,2012,26(12):1101-1102. |
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| 作者姓名： | 高飞 曹萍 董跃兰 杜鹏 吴颖 |
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| 作者单位： | 1. 云南省第一人民医院皮肤科,云南昆明,650032
2. 云南省第一人民医院妇科,云南昆明,650032 |
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| 基金项目： | 云南省科技厅应用基础计划项目 |
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| 摘 要： | 目的 探讨阴道分泌物中IL-4与IL-12的表达与复发性外阴阴道念珠菌病复发的关系。方法 ELISA法检测复发性外阴阴道念珠菌病(RVVC)患者组、外阴阴道念珠菌病(VVC)患者组阴道中IL-4,IL-12的表达水平,以正常女性白念珠菌携带者为对照组。结果 RVVC组的IL-4水平高于VVC组和对照组,差异有统计学意义(P<0.05),但3组的IL-12水平差异无统计学意义(P>0.05)。结论 IL-4表达差异可能与RVVC复发有关。
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| 关 键 词： | 白细胞介素-4 白细胞介素-12 复发性外阴阴道念珠菌病 |
The Level of IL-4 and IL-12 in Vaginal Secretion and Its Significance in RVVC Patients |
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| GAO Fei
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CAO Ping
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DONG Yue-lan
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DU Peng
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WU Ying.The Level of IL-4 and IL-12 in Vaginal Secretion and Its Significance in RVVC Patients[J].The Chinese Journal of Dermatovenereology,2012,26(12):1101-1102. |
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| Authors: | GAO Fei CAO Ping DONG Yue-lan DU Peng WU Ying |
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| Institution: | 1(1.Department of Dermatology,the First People’s Hospital,Yunnan Province,Kunming 650032,China;2.Department of Gynecology,the First People’s Hospital,Yunnan Province,Kunming 650032,China) |
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| Abstract: | Objective To detect the level of interleukin-4(IL-4) and interleukin-12(IL-12) in secretion of RVVC patients,VVC patients and normal control,and to investigate the relationship between secretion level and pathogenesis of RVVC.Methods The level of IL-4 and IL-12 in the vaginal secretion from VVC patient and RVVC patient were detected by ELISA and compare with that from normal controls.Results The vaginal secretion level of IL-4 in RVVC patients was higer than that in VVC patients and normal controls(P<0.05).For IL-12,there were no statistical difference among 3 groups(P>0.05).Conclusion The abnormal expression of IL-4 might participate in the pathogenesis of RVVC. |
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| Keywords: | Interleukin-4 Interleukin-12 Reeurrent vulvovaginalcandidiasis |
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