哺乳期妇女钙代谢及骨密度的变化

目的 由于优生优育工作的的不断进展，对于哺乳妇女有关钙代谢的研究逐渐引起人们的重视，我们对不同哺乳时限的妇女的钙代谢指标及骨密度等进行调查，了解哺乳对妇女钙代谢及骨密度的影响。方法 32例正常妇女为对照组，119例哺乳期妇女三个哺乳时段，根据哺乳时间分为哺乳0～3个月、6个月、8个月等各组。清晨空腹抽血，测定胫骨超声速率，并测定血清总钙及游离钙。结果 （1）血清总钙、游离钙：哺乳期妇女血清总钙低于对照组，并哺乳超过6个月下降明显，血清总钙降低8．8％。差异有显著性；血清游离钙变化不明显。（2）胫骨SOS：哺乳期妇女胫骨SOS值第一组与第二组变化不明显，哺乳超过6个月低于对照组，差异有显著性。胫骨SOS降低2．7％。结论 哺乳期胫骨SOS下降，作者所测得的皮质骨SOS结果只代表全身骨转换的一小部分，由此推断出哺乳期骨丢失是相当严重的。血钙下降明显，增加哺乳期妇女钙的摄人量，以期减少骨吸收，缓解骨密度的下降。

Correlative analyses of the tibia SOS and calcium metabolism in normal and lactation

Objective To explore the calcium metabolism in lactation women.Methods The lactation women were divided into 3 groups:(1)Suckle time 0~3 monthes(n=50);(2)Suckle time 6 monthes(n=40);(3)Suckle time 8 monthes(n=40);(4)Nonpregnant(n=32).Blood samples were collected at 8:00 a.m.following an overnight fast,in same day tibia SOS was measured by ultrasound scanner.Total calcium,free-calcium were measured.Results As compared with nonpregnant tibia SOS in lactation women declined,total calcium decreased.Conclusion As compared with nonpregnant the SOS in lactation women tibia decreased.