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肺表面活性剂在急性呼吸窘迫综合征中的作用
引用本文:林福清,邓小明. 肺表面活性剂在急性呼吸窘迫综合征中的作用[J]. 医学综述, 2006, 12(3): 129-131
作者姓名:林福清  邓小明
作者单位:第二军医大学长海医院麻醉科,上海,200433
摘    要:
肺表面活性物质(PS)在维持正常的肺功能起着重要作用,业已证明,PS异常与急性呼吸窘迫综合征(ARDS)的发病有关。关于外源性PS治疗ARDS的临床研究有很多,但其疗效文献报道相差很大,这可能与肺损伤程度PS制剂不同、给药途径、时机、剂量及机械通气有关。

关 键 词:肺表面活性剂  急性肺损伤  急性呼吸窘迫综合征
文章编号:1006-2084(2006)03-0129-03
收稿时间:2005-05-20
修稿时间:2005-11-11

Role of Pulmonary Surfactants in Acute Respiratory Distress Syndrome
LIN Fu-qing,DEN Xiao-ming. Role of Pulmonary Surfactants in Acute Respiratory Distress Syndrome[J]. Medical Recapitulate, 2006, 12(3): 129-131
Authors:LIN Fu-qing  DEN Xiao-ming
Affiliation:Department of Anesthesiology, Changhai Hospital affiliated to the Second Military Medical University, Shanghai 200433, China
Abstract:
Pulmonary surfactants(PS) is important to maintain the normal lung function,and surfactant alterations have been implicated in the pathophysiology of acute respiratory distress syndrome(ARDS).There have been many case reports and uncontrolled studies evaluating exogenous surfactant in patients with ARDS,but they have got different results.The potential causes include the severity of the injury at the time of treatment,the variable surfactant preparations,dosing regimes,and delivery methods used in different trials.
Keywords:Pulmonary surfactants   Acute lung injury   Acute respiratory distress syndrome
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