我院住院患者头孢菌素类药物利用分析

目的：了解医院头孢菌素类药物的使用情况及其合理性，促进临床合理用药。方法：根据医院计算机药品信息管理系统的原始数据资料，采用世界卫生组织（WHO）推荐的限定日剂量法，以限定日剂量（DDD）、用药频度（DDDs）、药物利用指数（DUI）为指标对2007年我院住院患者头孢菌素类药物使用情况进行统计分析。结果：2007年我院住院患者应用头孢菌素类药物有25个品种，占总抗菌药金额的59．39％，其中，第三代头孢菌素类药物及其复方制剂和氧头孢烯类药物销售金额占75．14％，成为临床治疗的主导药物。结论：2007年我院住院患者应用头孢菌素类药物基本合理，应严格控制第三代头孢菌素类药物及其复方制剂的应用，掌握用药指征，以提高疗效，延缓细菌耐药。

Analysis of the Utilization of Cephalosporins in Inpatients of Our Hospital

Objective： To investigate the rationality and situation of cephalosporins used in our hospital, and to promote rational drug use in clinic. Methods： By using the original data of hospital＇s drug information management system, the indexes including DDD, DDDs and DUI proposed by WHO were analyzed by defined daily dose. Results： There were 25 kinds of cephalosporins, accounting for 59.39% of the total antibacterial agents used in our hospital. It is indispensable to control the serious infection. The third generation of cephalosporins and its compound preparations and oxacephems accounted for 75.14% of the total and had become the leading drug in clinical therapy. Conclusion： The application of cephalosporins is almost rational in our hospital. The application of the third generation of cephalosporins and its compound preparation must be strictly controlled. Moreover, the drug indication should be mastered to improve effect and delay bacterial resistance.