| 大肠癌患者血清中巨噬细胞抑制因子-1升高的临床价值研究 |
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| 引用本文： | 王小兵,付超,田海梅,李艳芬,李茉,程冬婉,常青云,刘珊,齐军,张伟.大肠癌患者血清中巨噬细胞抑制因子-1升高的临床价值研究[J].癌症进展,2011,9(4):374-378,373. |
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| 作者姓名： | 王小兵 付超 田海梅 李艳芬 李茉 程冬婉 常青云 刘珊 齐军 张伟 |
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| 作者单位： | 中国医学科学院,北京协和医学院,肿瘤医院生物检测中心,北京,100021;中国医学科学院,北京协和医学院,肿瘤医院检验科,北京,100021 |
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| 基金项目： | 国家高技术研究发展863计划资助项目 |
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| 摘 要： | 目的 探讨巨噬细胞抑制因子1(MIC-1)在大肠癌诊断和早期诊断、治疗监测及复发预警中的临床价值.方法 应用自主研制的MIC-1检测试剂盒检测239例不同临床分期的大肠癌患者、16例肠道良性疾病患者及200例健康人血清样本中MIC-1水平,并对部分肿瘤患者进行连续监测;应用罗氏Cobas 601电化学发光免疫分析仪检测...
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| 关 键 词： | 巨噬细胞抑制因子-1 肿瘤标志物 大肠癌 临床价值 |
Application of serum macrophage inhibitory cytokine-1 in colorectal cancer |
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| Wang Xiaobing,Fu Chao,Tian Haimei,Li Yanfen,Li Mo,Cheng Dongwan,Chang Qingyun,Liu Shan,Qi Jun,Zhang Wei.Application of serum macrophage inhibitory cytokine-1 in colorectal cancer[J].Oncology Progress,2011,9(4):374-378,373. |
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| Authors: | Wang Xiaobing Fu Chao Tian Haimei Li Yanfen Li Mo Cheng Dongwan Chang Qingyun Liu Shan Qi Jun Zhang Wei |
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| Institution: | Wang Xiaobing1 Fu Chao2 Tian Haimei1 Li Yanfen1 Li Mo1 Cheng Dongwan1Chang Qingyun1 Liu Shan1 Qi Jun2 Zhang Wei1 1 Detection Center of Tumor Biology,2Clinical Laboratory,Cancer Institute & Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100021,China |
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| Abstract: | Objective To investigate the clinical value of macrophage inhibitory cytokine-1(MIC-1)in diagnosis,early diagnosis,treatment monitoring and recurrence warning of colorectal cancer.Methods Serum samples form 239 patients with different clinical stages of colorectal cancer,16 patients with benign bowel disease and 200 healthy human were detected by self-made MIC-1 assay kit for MIC-1 level.And some of tumor patients are followed up.CEA and CA19-9 were analyzed by Roche Cobas 601 ECL analyzer.Results MIC-1 lev... |
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| Keywords: | macrophage inhibitory cytokine-1 tumor marker colorectal cancer clinical value |
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