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| 2007-2010年肿瘤患者感染的病原菌分布及耐药性分析 | |
| 引用本文： | 张肖,夏文颖,严佳斌,张杰,梅亚宁,顾兵,刘根焰,潘世扬. 2007-2010年肿瘤患者感染的病原菌分布及耐药性分析[J]. 中华医院感染学杂志, 2011, 21(24): 5295-5298 |
| 作者姓名： | 张肖 夏文颖 严佳斌 张杰 梅亚宁 顾兵 刘根焰 潘世扬 |
| 作者单位： | 1. 江苏盛泽医院检验科,江苏吴江215228;南京医科大学第一附属医院检验科,江苏南京210029 2. 南京医科大学第一附属医院检验科,江苏南京,210029 3. 江苏盛泽医院检验科,江苏吴江,215228 |
| 基金项目： | 国家自然基金项目(81000754); 江苏省实验诊断学重点实验室重大课题(XK200731) |
| 摘 要： | 目的 了解2007-2010年南京医科大学第一附属医院血液科及肿瘤科肿瘤患者感染病原菌分布及耐药性规律,指导临床用药.方法 采用API鉴定系统鉴定细菌及真菌,纸片扩散法测定细菌药物敏感性,Rosco纸片法测定真菌对抗真菌药物敏感性；WHONET5.5软件进行统计分析.结果 2007-2010年血液科及肿瘤科肿瘤患者感染后共分离病原菌379株和237株；血液科肿瘤患者感染前3位病原菌依次为大肠埃希菌、表皮葡萄球菌、肺炎克雷伯菌,检出率分别为13.5％、11.9％、11.1％；肿瘤科肿瘤患者感染前3位病原菌依次为大肠埃希菌、肺炎克雷伯菌、白色假丝酵母菌,检出率分别为19.4％、10.5％、9.7％；未发现耐万古霉素葡萄球菌,但对其他多种抗菌药物耐药；肠杆菌科细菌对亚胺培南、美罗培南、头孢哌酮/舒巴坦和哌拉西林/他唑巴坦较敏感；非发酵菌对环丙沙星和头孢哌酮/舒巴坦较敏感,但对其他抗菌药物耐药性较高.结论 血液科及肿瘤科肿瘤患者感染病原菌对多种抗菌药物耐药性较高,应引起重视,加强抗菌药物合理使用. |
| 关 键 词： | 病原菌 细菌耐药 血液科 肿瘤科 |
Distribution of pathogens in tumor patients with infection and their antibiotic resistance |
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| ZHANG Xiao , XIA Wen-ying , YAN Jia-bin , ZHANG Jie , MEI Ya-ning , GU Bing , LIU Gen-yan , PAN Shi-yang. Distribution of pathogens in tumor patients with infection and their antibiotic resistance[J]. Chinese Journal of Nosocomiology, 2011, 21(24): 5295-5298 | |
| Authors: | ZHANG Xiao XIA Wen-ying YAN Jia-bin ZHANG Jie MEI Ya-ning GU Bing LIU Gen-yan PAN Shi-yang |
| Affiliation: | ZHANG Xiao,XIA Wen-ying,YAN Jia-bin,ZHANG Jie,MEI Ya-ning,GU Bing,LIU Gen-yan,PAN Shi-yang (Jiangsu Shengze Hospital,Wujiang,Jiangsu 215228,China) |
| Abstract: | OBJECTIVE To determine the distribution of pathogens in tumor patients with infection among hematology and oncology departments and their antibiotic resistance from the first Affiliated Hospital of Nanjing Medical University from 2007 to 2010. METHODS API detection system was used to identify bacteria and fungi.Disk diffusion susceptibility test was used to determine the antimicrobial susceptibility,Rosco disk diffusion method was used to determine the antifungal susceptibility,and results were analyzed by ... |
| Keywords: | Pathogens Bacterial resistance Hematology department Oncology department |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |