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| 虎耳草的化学成分研究 | |
| 引用本文： | 先春,龚小见,赵超,周欣,杨占南,王垄. 虎耳草的化学成分研究[J]. 中国实验方剂学杂志, 2012, 18(10): 124-126 |
| 作者姓名： | 先春 龚小见 赵超 周欣 杨占南 王垄 |
| 作者单位： | 1. 贵州师范大学天然药物质量控制研究中心,贵阳550001;贵州大学精细化工研究开发中心,贵阳550025 2. 贵州师范大学天然药物质量控制研究中心,贵阳550001;贵州师范大学贵州省山地环境信息系统与生态环境保护重点实验室,贵阳550001 3. 贵州师范大学贵州省山地环境信息系统与生态环境保护重点实验室,贵阳,550001 |
| 基金项目： | 贵州省中药现代化科技产业研究开发专项项目(黔科合中药字[2010]5023 号);贵阳市科学技术计划项目([2010]筑科 计 合同字第3-重-1号);贵阳市科学技术计划项目([2010]筑科合同字第1-中-23号);贵州省科技创新人才团队建设项目(黔科合人才团队[2011]4008) |
| 摘 要： | 目的:研究虎耳草石油醚萃取部分和乙酸乙酯萃取部分的化学成分.方法:虎耳草全草用80％乙醇提取后,依次用石油醚,乙酸乙酯,正丁醇萃取,对石油醚萃取部分和乙酸乙酯萃取部分采用硅胶柱色谱、凝胶柱色谱等手段进行分离、纯化,根据理化性质和波谱数据进行结构鉴定.结果:从虎耳草的石油醚层和乙酸乙酯层分离得到10个化合物,分别为:β-谷甾醇(1),三十一烷醇(2),十八碳酸单甘油酯(3),胡萝卜苷(4),5α,8α-过氧化麦角甾-6,22-二烯-3β-醇(5),二十四烷酸(6),对-香豆酸(7),没食子酸(8),槲皮素(9),岩白菜素(10).结论:其中化合物2～7为首次从该植物中分离得到. |
| 关 键 词： | 虎耳草 化学成分 结构鉴定 |
| 收稿时间： | 2011-12-02 |
Chemical Constituents of Saxifraga stolonifera |
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| XIAN Chun,GONG Xiao-jian,ZHAO Chao,ZHOU Xin,YANG Zhan-nan and WANG Long. Chemical Constituents of Saxifraga stolonifera [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2012, 18(10): 124-126 | |
| Authors: | XIAN Chun GONG Xiao-jian ZHAO Chao ZHOU Xin YANG Zhan-nan WANG Long |
| Affiliation: | Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;Fine Chemicals Research and Development Center, Guizhou University, Guiyang 550025, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;Fine Chemicals Research and Development Center, Guizhou University, Guiyang 550025, China |
| Abstract: | Objective:To study the chemical constituents from the PE extract and the EtOAc extract of Saxifraga stolonifera.Method: Saxifraga stolonifera was extracted with 80% ethanol and isolated by petroleum ether,ethyl acetate,n-butanol.Chromatographic techniques were applied to separate and purify the compounds from the PE extract and the EtOAc extract,and their structures were confirmed on the basis of physicochemical properties and spectral data.Result: Ten compounds from the PE extract and the EtOAc extract were isolated and identified as β-sitosterol(1),1-hentriacontanol(2),glyceryl monostearate(3),daucosterol(4),5α,8α-epid-ioxyergosta-6,22-dien-3β-ol(5),tetracosane acid(6),p-coumaric acid(7),gallic acid(8),quercetin(9),bergenin(10).Conclusion: Compounds 2~7 were isolated from this plant for the first time. |
| Keywords: | Saxifraga stolonifera chemical constituent structure elucidate |
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