杜仲腰痛丸治疗腰椎间盘突出症的临床研究

目的:评价杜忡腰痛丸治疗腰椎间盘突出症的临床疗效、安全性。方法:取腰椎间盘突出症患者400例,随机分为杜仲腰痛丸治疗组300例(治疗组),伸筋丹胶囊治疗组100例(对照组),观察治疗前后症状。体征、影像学变化及临床效果。结果:治疗后两组腰背部疼痛与不适、下肢疼痛与麻木、工作生活能力、下肢功能、脊柱活动度与椎旁触压放射痛及直腿抬高和加强试验、感觉均有显著改善(P<0.01),治疗组改善优于对照组(P<0.01):两组治疗前后调线示椎间隙无明显变化(P>0.05):治疗组疗效优于对照组(P<0.05),发病时间短者(治疗组),疗效较好(P<0.01)。结论:杜仲腰痛丸无毒副作用,是一种治疗腰椎间盘突出症较好的药物。

A clinical study on treating lumbar intervertebral disc herniation with duzhongyaotong wan

Objective:To evaluate therapeutic effectiveness and safety of duzhongyaotong wan on lumbar intervertebral disc herniation.Methods:400 cases of lumbar intervertebral disc hemiation were divided randomly into treatment group(300 cases,treated with duzhongyaotong wan) and control group(100 cases,treated with shenjin dan).Fore-and-after treatment change of symptom,physical sign,X-ray and clinical effect of the all patients were analyzed.Results:The changes of the pain and upset waist and back,lower limb ache and numb,ability of work and life,lower limb function,spine activity,radiating pain of paravertebra pressed and leg elevation and strengthen test,Feel in the both of groups were significant better(P<0.01).after the treatment.Improvement in treatment group was better than in the control group(P<(0.01)).The changes of intervertebral space on X-ray were not difference after treatment in both groups(P>0.05).The effect of treatment of group was significant difference from that of control group(P<0.05).If course of diseases were short,effect was better(P<0.01).Conclusions:Duzhongyaotong wan has no toixic side effect,is a kind of better druggery for treating lumbar intervertebral disc herniation.