肠易激综合征患者直肠肛门动力学研究

为了研究肠易激综合征患者肛门运动功能，我们测定了５０例ＩＢＳ患者在１１例正常人直肠肛门压力衣排便功能；发现：（１）直肠静息压，肛门括约肌静息压及其最大缩窄压在ＩＢＳ腹泻组，便秘组及正常对照组组均无显著差异。（２）肛管高压带长度在ＩＢＳ腹泻组及便秘组均显著高于正常对照组。（３）直肠壶腹部的感觉阈值，最大耐受量等，在ＩＢＳ腹泻组均显著低于正常对照组。（４）ＩＢＳ便秘组感觉阈值与正常对照组差异，但其最大

Ano-retal Motility in the Irritable Bowel Syndrome

To study the rectoanal function in patients with irritable bowel syndrome (IBS), the rectoanal manometry were performed on 50 patients with diarrhea predominant type IBS (Dp-IBS), 20 patients with constipation predominant type IBS (Cp-IBS) and 11 normal subjects. The results showed: (1)The rectal resting pressure, the anal resting pressure and the maximum squeeze pressure of the anal sphincter were not different among the patients with Dp-IBS, Cp-IBS and normal subjects (P >0.05). (2)The length of high pressure zone in the patients with Dp-IBS and Cp-IBS were significantly higher than that in normal subjects (P<0. 0005). (3)The rectal sensitivity, maximum tolerance etc, in Dp-IBS were significantly lower than that in normal subjects (P < 0. 005 ~0. 0005). (4)The rectal sensitivity was not different between patients with Cp-IBS and normal subjects (P>0.05); The maximum tolerance and the rectal capacity causing rectoanal inhibitory reflex in patients with Cp-IBS were significantly higher than normal subjects (P<0.05). These results suggested: At resting state, the function of rectal and anal sphincter in patients with-IBS were normal, but its defecation function and rectal sensitivity were disordered.