| 近红外技术应用于药厂丹参药材质量检测 |
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| 引用本文： | 白雁,李磊,雷敬卫,谢彩侠,左春芳.近红外技术应用于药厂丹参药材质量检测[J].中国现代应用药学,2012,29(3):222-225. |
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| 作者姓名： | 白雁 李磊 雷敬卫 谢彩侠 左春芳 |
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| 作者单位： | BAI Yan, LI Lei, LEI Jingwei*, XIE Caixia, ZUO Chunfang |
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| 基金项目： | 河南省重大公益科研项目(081100912500)；河南中医学院2011年博士科研基金(BSJJ2011-03) |
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| 摘 要： | 目的利用近红外光谱技术,快速测定丹参药材中丹参酮ⅡA的含量。方法运用偏最小二乘法(PLS)建立丹参药材中丹参酮ⅡA含量与其近红外光谱之间的校正模型,并对未知的丹参样品进行丹参酮ⅡA含量预测。结果校正集内部交叉验证决定系数R2为0.996 94,交互验证均方根偏差RMSECV为0.011 8,11份样品的外部预测均方根偏差RMSEP为0.023 7。预测值的平均相对误差为1.712 9%。结论近红外光谱技术测定丹参药材中丹参酮ⅡA的含量是可行的,该方法快速准确、简单无损,可应用于大批量样品的快速分析。
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| 关 键 词： | 近红外光谱技术 丹参提取物 丹参酮ⅡA 快速测定 |
| 收稿时间： | 2011/9/29 0:00:00 |
| 修稿时间： | 12/3/2011 3:10:12 PM |
Quality Determination of Salvia Miltiorrhiza in Pharmaceutical Industry By Near-infrared Spectroscopy |
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| BAI Yan,LI Lei,LEI Jingwei,XIE Caixia,ZUO Chunfang.Quality Determination of Salvia Miltiorrhiza in Pharmaceutical Industry By Near-infrared Spectroscopy[J].The Chinese Journal of Modern Applied Pharmacy,2012,29(3):222-225. |
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| Authors: | BAI Yan LI Lei LEI Jingwei XIE Caixia ZUO Chunfang |
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| Institution: | Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China |
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| Abstract: | OBJECTIVE To rapidly determine the content of tanshinoneIIA in Salvia miltiorrhiza extraction by near-infrared spectroscopy. METHODS The calibration model of the content of tanshinone II A in Salvia miltiorrhiza and the near infrared spectroscopy of Salvia miltiorrhiza was built with partial least squares. RESULTS The correlation coefficient of calibration （R2） was 0.996 94. Root mean square error of cross validation （RMSECV） was 0.011 8, and external prediction deviation RMSEP of 11 samples was 0.023 7. Predicted average relative error was 1.712 9%. CONCLUSION It is feasible to determine the tanshinone II A content in Salvia miltiorrh. Near-infrared spectroscopy is fast, accurate, simple and nondestructive which can be applied in rapid analysis of large numbers of samples. |
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| Keywords: | near-infrared spectroscopy Salvia miltiorrh Tanshinone II A rapid determination |
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