Analgesic and diuretic properties of α‐santalone from Polygonum flaccidum |
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| Authors: | Abdul Mazid Md. Bidyut K. Datta Lutfun Nahar Abdur Rashid Md. Sitesh C. Bachar S. A. M. Khairul Bashar Satyajit D. Sarker |
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| Affiliation: | 1. Phytopharmacology Research Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh;2. Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh;3. Drug Discovery and Design Research Division, Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, City Campus South, MA Building, Wulfruna Street, Wolverhampton WV1 1LY, UK;4. Department of Pharmacy, North South University, Kamal Ataturk Avenue, Banani, Dhaka 1213, Bangladesh;5. Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, MM Building, Molineux Street, Wolverhampton WV1 1SB, UK |
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| Abstract: | ![]()
Polygonum flaccidum Meissn. is an annual herb, native to Bangladesh, and well known for its analgesic, anti‐inflammatory, diuretic, purgative and insecticidal properties, and also for its use against snake‐bites. The analgesic and the diuretic properties of α‐santalone (1), isolated from the aerial parts of Polygonum flaccidum, were assessed by the acetic‐acid‐induced writhing method and the Lipschitz test, respectively. Complete 1H and 13C NMR data of 1 are also presented. Copyright © 2010 John Wiley & Sons, Ltd. |
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| Keywords: | Polygonum flaccidum Polygonaceae α ‐santalone analgesic diuretic NMR |
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