| CIK细胞对S180及H-22抑瘤作用的实验比较 |
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| 引用本文： | 李淑艳,任欢,杨凤坤,富东旭,高翔,邢淑贤,李殿俊. CIK细胞对S180及H-22抑瘤作用的实验比较[J]. 医学研究杂志, 2002, 31(10): 44-46 |
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| 作者姓名： | 李淑艳 任欢 杨凤坤 富东旭 高翔 邢淑贤 李殿俊 |
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| 作者单位： | 1. 齐齐哈尔医学院生化教研室
2. 哈尔滨医科大学 |
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| 摘 要： | 目的观察CIK(cytokine induced killer)细胞对S180和H-22荷瘤鼠的抑制肿瘤作用。方法建立S180和H-22荷瘤鼠动物模型,静脉输入CIK细胞做抗肿瘤治疗,同时设LAK对照,用同位素法检测经治疗后荷瘤鼠T细胞增殖及NK细胞毒活性。结果 CIK细胞对S180和H-22荷瘤鼠的抗肿瘤作用显著强于LAK细胞。结论 CIK细胞对S180和H-22荷瘤鼠有明显的抗肿瘤作用,并且优于LAK细胞。
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| 关 键 词： | CIK细胞 S180 H-22 抗肿瘤作用 |
| 修稿时间： | 2002-06-06 |
Anti - tumor activity of CIK cells on the mice bearing S180 and H - 22 tumor in vivo. |
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| Li Shuyan,Ren Huan,YangFengkun,Fu Dongxu,Gao Xiang,Xing Shuxian,Li Dianjun. Anti - tumor activity of CIK cells on the mice bearing S180 and H - 22 tumor in vivo.[J]. Journal of Medical Research, 2002, 31(10): 44-46 |
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| Authors: | Li Shuyan Ren Huan YangFengkun Fu Dongxu Gao Xiang Xing Shuxian Li Dianjun |
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| Abstract: | Objective To evaluate the anti - tumor activity of CIK (cytokine induced killer) cells on mice bearing S180 and H - 22 tumor in vivo. Methods CIK cells were injected intravenously into the mice bearing S180 and H - 22 tumor and compared with LAK controls in the same time. Results CIK cells had significantly anti - tumor effect which was much higher than that of LAK cells. Conclusion CIK cells had significantly anti - tumor effect on mice bearing S180 and H - 22 tumor in vivo than that of LAK. |
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| Keywords: | CIK S180 H-22 Anti - tumor effect |
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