健脾生血颗粒治疗老年人缺铁性贫血临床观察

目的:观察健脾生血颗粒治疗老年人缺铁性贫血的临床疗效及作用机制。方法:将80例符合缺铁性贫血的老年患者随机分为2组。对照组32例,给予福乃得口服治疗。治疗组48例,给予健脾生血颗粒口服。2组连续治疗30 d后观察有效率及RBC、Hb、MCV、MCH、MCHC、血清铁、总铁结合力指标变化。结果:治疗组临床总有效率明显高于对照组(P0.05)。2组治疗后RBC、Hb、MCV、MCH、MCHC、血清铁、总铁结合力均有显著改善,但2组治疗后指标比较无统计学意义(P0.05)。结论:健脾生血颗粒治疗老年人缺铁性贫血疗效显著,值得临床推广应用。

Clinical Observation on Jianpi Shengxue Granule in the Treatment of Elderly Patients with Iron Deficiency Anemia

To observe the clinical effect and the mechanism of Jianpi Shengxue Granule in the treatment of elderly patients with iron deficiency anemia. Methods:Eighty elderly patients with iron deficiency anemia who meet with inclusive criteria were selected and randomly divided into two groups, namely the control group (32 patients) with Funaide oral liquid and the treatment group (48 patients) with Jianpi Shengxue Granule. The efficacy was observed after 30 days in two groups. Results:The total effective rate of treatment group was better than that of control group (P<0.05). The RBC, Hb, MCV, MCH, MCHC, serum iron and TIBC were obviously improved after the treatment compared with those before treatment (P<0.05) but without significant difference between the two groups after treatment (P>0.05). Conclusion:Jianpi Shengxue Granule may have good cure effect on iron deficiency anemia in elderly patients and it is worthy of clinical use.