参梅健胃胶囊制备工艺研究

目的:对参梅健胃胶囊制备工艺进行研究。方法:采用水蒸汽蒸馏法提取挥发油,以挥发油收率为指标,考察浸泡时间、加水量、蒸馏时间对提取工艺的影响。采用L9(34)正交试验,以出膏率、柚皮苷含量为考察指标,对水煎提取工艺的主要因素—加水量、煎煮次数、提取时间进行考察。结果:药材加水5倍,浸泡4 h,蒸馏7 h提取挥发油;水煎工艺为煎煮2次,加水量分别为6倍、4倍,时间为2 h。结论:研究结果能够作为参梅健胃胶囊的制备工艺,并可以应用于产业化中。

Preparation Research on Shenmei Jianwei Capsule

To study Shenmei Jianwei capsule preparation technology. Methods:The volatile oils were extracted by steam distillation. The volatile oil yield was taken as examining index to investigate the influence of soak time, additive quantity of water and distillation time on extraction process. In order to extract rate and the content of naringin as examining index, main factors of water decoction extraction process, water content, decoction time and extraction time were examined By L9 (34) orthogonal test. Results:Add 5 times of water than herbs, then soak the herbs for 4 hours and distillate them 7 hours to extract the volatile oil. Water extraction 2 times, add water 6 times and 4 times higher than the amount of herbs respectively. Extraction lasts 2 hours. Conclusion:The results can be used in preparing Shenmei Jianwei capsule, and can be applied to production.