参芎葡萄糖注射液治疗冠心病的临床研究

目的:观察参芎葡萄糖注射液对冠状动脉粥样硬化性心脏病患者的疗效及机制分析。方法:随机选取104例冠心病患者将其分为对照组和治疗组,每组52例,对照组应用稳定板块、抗血小板聚集等西医常规治疗,治疗组在对照组的基础上静脉滴注参芎葡萄糖注射液100 m L,2次/d。结果:对照组有效率为63.46%,治疗组有效率为86.53%,2组有效率比较,差异有统计学意义(P0.05)。治疗组治疗后血脂脂代谢和缺血修饰白蛋白(IMA)较治疗前有明显改善,与对照组治疗后比较,差异有统计学意义(P0.05)。结论:参芎葡萄糖注射液治疗冠心病临床疗效显著,其治疗机制主要体现在影响血脂代谢、改善冠脉供血和降低血液黏度等方面。

Clinical Observation on the Effect of Shenxiong Glucose Injection in Treating Coronary Heart Disease

To analyze the effect and mechanism of Shenxiong glucose injection in treating coronary heart disease (CHD).Methods:A total of 104 patients with CHD were divided into control group and treatment group according to random number table with 52 cases in each group.The control group was treated by conventional western medicine,such as stable plaques,anti platelet aggregation,and so on.The treatment group was treated by Shenxiong glucose injection 100 mL on the basis of medication of the control group,twice a day.Results:The effective rate was 63.46% in control group and 86.53% in treatment group,and the difference was statistically significant (P<0.05).The lipid metabolism and IMA of treatment group were obviously improved compared with before treatment.Also,compared the improvements of the control group,the difference was statistically significant (P<0.05).Conclusion:Shenxiong Glucose injection in the treatment of CHD has distinct clinical curative effect.Its treatment mechanism is mainly manifested by its effect on lipid metabolism,improving the coronary blood supply and reducing blood viscosity.