中西医结合治疗排卵障碍性不孕症疗效观察及其安全性评价

目的:探讨中西医结合治疗排卵障碍性不孕症疗效观察及其安全性评价。方法:选取2013年5月至2016年4月我院排卵障碍性不孕症患者126例,根据其治疗方法分为中西医结合观察组(n=62),西药观察组(n=64),统计2组患者治疗前后的子宫内膜厚度,观察分析2组的排卵率、妊娠率、流产率及治疗总有效率,并结合其不良反应发生率对其安全性作系统的评价。结果:治疗前中西医结合观察组的子宫内膜厚度与西药观察组比较,差异无统计学意义(P0.05),治疗后,中西医结合观察组的子宫内膜厚度与西药观察组比较增大(P0.05);中西医结合观察组的排卵率、妊娠率、流产率均比西药观察组高(P0.05);而中西医结合观察组的治疗总有效率90%与西药观察组81.25%比较差异无统计学意义(P0.05),但其治愈率比西药观察组高(P0.05);中西医结合观察组的的不良反应发生率9.68%与西药观察组的不良反应发生率10.94%比较差异无统计学意义(P0.05)。结论:中西医结合可以提高治疗排卵障碍性不孕症的排卵率、妊娠率及治疗总有效率,是一种安全可靠的治疗方法,值得临床上推广应用。

Efficacy and Safety of Integrated Traditional Chinese and Western Medicine in Ovulatory Infertility

To explore the efficacy and safety of integrated traditional Chinese and Western medicine in the treatment of ovulatory infertility. Methods:In total, 126 cases of infertility patients who came to our hospital from May 2013 to April in were divided into a treatment group (n=62) and a western medicine group (n=64) according to the treatment method. Endometrial thickness in the two groups before and after treatment were statistically analyzed. The ovulation rate, pregnancy rate, abortion rate and the total effective rate of the two groups were observed and analyzed,and then evaluated combined with the adverse reaction rate for its security. Results:Before treatment, the endometrial thickness of the combined therapy group were compared with western medicine treatment group, and there was no statistically significant difference (P>0.05). After treatment, the endometrial thickness of the combined therapy group was increased compared with that of the western medicine group (P<0.05); The ovulation rate, abortion rate and pregnancy rate of the combination group were higher than those of the simple western medicine group (P<0.05);While the combined therapy group, the total effective rate was 90% compared with the western medicine treatment group 81.25% (P>0.05), but the cure rate was higher than that of the western medicine group (P<0.05);The incidence of adverse reactions in the integrated therapy group was 9.68%, and the incidence rate of adverse reactions was 10.94% in the western medicine group, showing no difference between the two groups (P>0.05).Conclusion:The combination of traditional Chinese and Western medicine can improve the ovulation rate, pregnancy rate and total effective rate of treatment, and it is a safe and reliable treatment method, which is worthy of clinical application.