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高磷血症致慢性肾脏病血管钙化的研究及治疗进展
引用本文:石凯峰,张宁,刘世巍,柳诗意,李韶菁.高磷血症致慢性肾脏病血管钙化的研究及治疗进展[J].世界中医药,2017(2).
作者姓名:石凯峰  张宁  刘世巍  柳诗意  李韶菁
作者单位:1 中国中医科学院望京医院,北京,100102; 2 中国中医科学院中药研究所,北京,100700
基金项目:国家自然科学基金项目(编号:81273747)
摘    要:血管钙化是心血管疾病中最常见的病理表现,已经成为慢性肾脏病(Chronic Kidney Disease,CKD)的主要死亡原因,也是慢性肾脏病心血管疾病高发的独立危险因素,高磷血症是慢性肾脏病的常见并发症,高磷可通过多种机制或途径参与血管钙化的发生发展,与慢性肾脏病心血管死亡率密切相关,本文就高磷血症引起血管钙化的机制及中西医治疗作一综述。

关 键 词:慢性肾脏病  高磷血症  血管钙化  治疗
收稿时间:2016/3/25 0:00:00

Progresses and Research in the Treatment of Vascular Calcification in Chronic Kidney Disease Induced by Hyperphosphatemia
Shi Kaifeng,Zhang Ning,Liu Shiwei,Liu Sshiyi,Li Shaojing.Progresses and Research in the Treatment of Vascular Calcification in Chronic Kidney Disease Induced by Hyperphosphatemia[J].World Chinese Medicine,2017(2).
Authors:Shi Kaifeng  Zhang Ning  Liu Shiwei  Liu Sshiyi  Li Shaojing
Institution:1 Wangjing Hospital of China Academy of Chinese Medical Science, Beijing 100102, China; 2 Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
Abstract:Cardiovascular disease has become the leading cause of death among patients with chronic kidney disease (CKD), and vascular calcification is the most commonly seen pathological change. Vascular calcification is an independent risk factor in cardiovascular disease induced by CKD. Hyperphosphatemia is a common complication of chronic kidney disease. High phosphorus can participate in the development of vascular calcification through a variety of mechanisms or pathways. And it is closely related to the mortality of patients with CKD and cardiovascular. In this paper, the vascular calcification mechanism caused by hyperphosphatemia and its treatment in western medicine and Traditional Chinese medicine are reviewed.
Keywords:Chronic kidney disease  Hyperphosphatemia  Vascular calcification  Treatment
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