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Circadian variations of melatonin concentration in saliva and blood content of immunocompetent cells in healthy individuals
Authors:Litvinenko G I  Shurlygina A V  Malysheva O A  Kudaeva O T  Shirinskii V S  Kozlov V A  Trufakin V A
Affiliation:(1) Institute of Clinical and Experimental Lymphology, Institute of Physiology, Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk
Abstract:
Salivary content of melatonin and parameters of the immune status were studied in young healthy individuals. Morning and evening levels of melatonin showed different correlations with some immunity parameters. It was assumed that the degree and type of correlation between the immune system and melatonin depend on the phase of circadian cycle, which should be considered during evaluation of immunoendocrine status.
Keywords:immune status  melatonin  saliva  circadian cycle
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