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大肠腺癌和腺瘤AEG-1基因的表达及意义
引用本文:罗何三,董忠谊,邹金金,曾钦,吴德华. 大肠腺癌和腺瘤AEG-1基因的表达及意义[J]. 热带医学杂志, 2011, 11(4): 411-413,427
作者姓名:罗何三  董忠谊  邹金金  曾钦  吴德华
作者单位:南方医科大学南方医院放疗科,广东,广州,510515
基金项目:广东省自然科学基金,院长基金
摘    要:
目的 探讨AEG-1在大肠癌中的表达及其临床病理意义.方法 采用免疫组化的方法 检测60例正常大肠粘膜、22例大肠腺瘤和60例大肠腺癌中AEG-1的表达.结果 大肠腺癌和腺瘤中AEG-1的阳性率分别为91.7%和90.9%,明显高于正常大肠粘膜组织的23.3%,两者之间差异有统计学意义(P<0.001),其中大肠腺癌的...

关 键 词:AEG-1基因  基因表达  大肠肿瘤

Expression of AEG-1 gene in colorectal carcinoma and adenoma and its clinical significance
LUO He-san,DONG Zhong-yi,ZOU Jin-jin,ZENG Qin,WU De-hua. Expression of AEG-1 gene in colorectal carcinoma and adenoma and its clinical significance[J]. Journal Of Tropical Medicine, 2011, 11(4): 411-413,427
Authors:LUO He-san  DONG Zhong-yi  ZOU Jin-jin  ZENG Qin  WU De-hua
Affiliation:LUO He-san,DONG Zhong-yi,ZOU Jin-jin,ZENG Qin,WU De-hua (Department of Radiation Oncology,Nanfang Hospital,Southern Medical University,Guangdong Province,Guangzhou 510515,China)
Abstract:
Objective To investigate the expression of astrocyte elevated gene-1(AEG-1)in colorectal carcinoma and its clinical-pathological significance.Methods The expression of AEG-1 in normal colorectal tissues,adenoma and colorectal carcinoma was detected using immunohistochemical method.Results The positive rate of AEG-1 in the colorectal carcinoma was 91.7% and that in the adenoma was 90.9%.The result was significantly higher than the normal colorectal tissues.The difference between the two groups was significan...
Keywords:AEG-1 gene  gene expression  colorectal neoplasmas  
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