Inhibition of Expression of Hypoxia-inducible Factor-1α mRNA by Nitric Oxide in Hypoxic Pulmonary Hypertension Rats |
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作者单位: | Department of Pathology and Pathophysiology,Department of Obstetrics and Gynecology,Department of Pathology and Pathophysiology,Department of Pathology and Pathophysiology,Department of Pathology and Pathophysiology School of Basic Medical Sciences,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,School of Basic Medical Sciences,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,School of Basic Medical Sciences,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,School of Basic Medical Sciences,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030 |
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摘 要: | Hypoxiaisadirectfactorcausinghypoxicpul monaryhypertension (HPH) .hypoxiainduciblefac tor 1α (HIF 1α)isfoundtobethemostcrucialfactorsofarwhichmediatesthecellularresponsetohypoxi a1] .OurpreviousstudyrevealedthatoverexpressionofHIF 1andendothelin 1(ET 1…
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