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| 造釉细胞纤维瘤和造釉细胞纤维肉瘤增生活性研究 | |
| 引用本文： | 卢勇,高田隆,王炼,周志瑜,吴兰雁,赵明,二阶宏昌. 造釉细胞纤维瘤和造釉细胞纤维肉瘤增生活性研究[J]. 四川大学学报(医学版), 1998, 0(4) |
| 作者姓名： | 卢勇 高田隆 王炼 周志瑜 吴兰雁 赵明 二阶宏昌 |
| 作者单位： | 日本广岛大学齿学部 |
| 摘 要： | 采用增殖细胞核抗原（ＰＣＮＡ）的免疫组化染色，研究了６例造釉细胞纤维瘤（ＡＦ）和３例造釉细胞纤维肉瘤（ＡＦＳ）的上皮成分和间叶成分的增生活性。结果显示：ＡＦＳ肿瘤性间叶成分的ＰＣ－ＮＡ标记指数（４０．８％）显著高于ＡＦ（３．２％）（Ｐ＜０．０１）；在ＡＦＳ中，上皮成分的ＰＣＮＡ标记指数明显低于间叶成分（Ｐ＜０．０１）。由此提示，ＰＣＮＡ标记可作为鉴别ＡＦ与ＡＦＳ的一个有价值的指标。 |
| 关 键 词： | 口腔肿瘤 颌骨 牙源性肿瘤 造釉细胞纤维瘤 造釉细胞纤维肉瘤 增殖细胞核抗原 |
An Immunohistochemical Study of the Proliferating Activity of Ameloblastic Fibroma and Ameloblastic Fibrosarcoma |
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| Lu Yong Takashi Takata Wang Lian Zhou Zhiyu Wu Lanyan Zhao Ming Hiromasa Nikai. An Immunohistochemical Study of the Proliferating Activity of Ameloblastic Fibroma and Ameloblastic Fibrosarcoma[J]. Journal of Sichuan University. Medical science edition, 1998, 0(4) | |
| Authors: | Lu Yong Takashi Takata Wang Lian Zhou Zhiyu Wu Lanyan Zhao Ming Hiromasa Nikai |
| Affiliation: | Chengdu 610041 |
| Abstract: | Six cases of ameloblastic fibroma (AF) and three cases of ameloblastic fibrosarcoma (AFS) were immunohistochemically investigated with a proliferating cell nuclear antigen (PCNA) monoclone antibody. Data on the PCNA labeling index (LI) of both epithelial and mesenchymal components were analyzed. The results showed that the PCNA LI of mesenchymal component of AFS (40.8%) was significantly higher than that of AF (3.2%) ( P<0 01) and that of the epithelial component of AFS (5 3%) was significantly lower than that of the mesenchymal one of AFS ( P<0.01 ). The results suggested that PCNA LI be a useful marker for the differentiation diagnosis of AF and AFS. |
| Keywords: | Oral neoplasm Jaws Ameloblastic fibroma Ameloblastic fibrosarcoma PCNA |
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