早期限制性液体复苏在伴失血性休克脑伤中的疗效分析

目的评价积极液体复苏和限制性液体复苏对脑伤合并创伤失血性休克患者的治疗效果,改进治疗方法,提高治愈率。方法将53例脑伤合并创伤失血性休克患者随机分成积极液体复苏组（A组）与限制性液体复苏组（B组）进行治疗,比较两组患者的复苏液体使用量、抢救6小时后的pH及BE,并比较两组72小时及2周的死亡率情况。结果 A组的液体量用量（2631±247）ml,B组为（1483±178）ml,组间差异有显著性（P〈0.05）;而在胶体的用量、复苏6小时后的pH值及BE值无明显统计学差异（P〉0.05）。入院72小时A组死亡率为18.5%,B组为15.4%,组间无明显统计学差异（P〉0.05）。但2周死亡率,A组为48.1%,B组为34.6%,存在统计学差异（P〈0.05）。结论颅脑损伤伴创伤失血性休克患者行适当的限制性液体复苏可以改善预后。

Effect of early limited fluid resuscitation on craniocerebral injury accompanied with hemorrhagic traumatic shock

Objective To compare the effect of aggressive fluid resuscitation and limited fluid resuscitation on treatment of craniocerebral injury accompanied with hemorrhagic traumatic shock.Methods 53 patients with craniocerebral injury accompanied with hemorrhagic traumatic shock were randomly divided into aggressive fluid resuscitation group(A) and limited fluid resuscitation group(B).The fluid volume for recovery,the pH and BE six hours after rescue,and mortality were observed.Results The liquid volume of two groups were significant different in the dosage of the colloid.PH and BE value were no significant difference after recovery 6 hours.Mortality of two groups(A group was 18.5%,B group was 15.4%) in Hospital to 72 hours were no significant difference.2 weeks mortality existed visible statistical differences(A group was 48.1% and B group was 34.6%).Conclusion The limited fluid resuscitation may improve the prognosis of craniocerebral injury accompanied with hemorrhagic traumatic shock patients.