中医药治疗慢性阻塞性肺疾病急性加重期呼吸衰竭研究述评

目的：探讨中医药治疗慢性阻塞性肺疾病（Chronic Obstructive Pulmonary Disease,COPD）急性加重期呼吸衰竭的研究进展情况。方法：通过对近10 a来有关慢性阻塞性肺疾病急性加重（acute exacerbations of COPD,AECOPD）期呼吸衰竭的中医文献进行系统整理、归纳、分析。结果：目前AECOPD呼吸衰竭的病因病机、证候分类、诊断标准及治疗等方面尚不规范,临床研究设计方法有待进一步加强,疗效评价指标及方法有待进一步提高等。故应着眼于病机规律、证候规范等方面的研究,并在此基础上提高临床理论设计水平,开展多中心、大样本的临床研究以提供高级别的临床证据,为中医药临床应用的进一步研究提供科学依据。结论：中医药治疗AECOPD期呼吸衰竭的临床效果较好,并为AECOPD期呼吸衰竭临床治疗和科研提供依据。

Research Comment on the Treatment of Respiratory Failure of Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Chinese Medicine

Objective ：To explore the research progress of treating respiratory failure of Acute Exacerbation of Chronic Obstructive Pulmo nary Disease （AECOPD） by Chinese medicine. Methods ： TCM literatures about respiratory failure of AECOPD in recent ten years were systematically collected, concluded and analyzed. Results： Pathogenesis law, syndrome classification, diagnosis criterion and application of respiratory failure of AECOPD still showed a lack of standardization at present and design procedures of clinical research needed to be further strengthened. Evaluation index and methods of curative effect needed to be further improved. Therefore, research should be fo cused on the law of pathogenesis, standardization of syndrome, and so on, and improving the design level of clinical theory based on that. Clinical research with multicenter and great amount of samples should be developed to provide highlevel clinical evidence so that to provide scientific basis for the clinical application of Chinese medicine. Conclusion：Traditional Chinese medicine has good clinical effect on the treatment of respiratory failure of AECOPD, which provides evidence for the clinical treatment and scientific research of re spiratory failure of AECOPD.