| 肝细胞癌组织中HBsAg、AFP的研究 |
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| 引用本文： | 常家聪,刘弋,宋海屏,王瑞祥. 肝细胞癌组织中HBsAg、AFP的研究[J]. 中国普通外科杂志, 1996, 0(1) |
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| 作者姓名： | 常家聪 刘弋 宋海屏 王瑞祥 |
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| 作者单位： | 安徽医科大学附属医院外科 230022(常家聪，刘弋，宋海屏)，安徽医科大学附属医院外科 230022(王瑞祥) |
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| 摘 要： | 本研究对65例肝细胞癌标本进行免疫组化测定组织细胞中的HBsAg和AFP,结果显示肝癌细胞中存在有HBsAg、AFP,二者都主要存在于细胞浆中,表示HBV·DNA可以表达HBsAg抗原,致使肝细胞产生AFP,促发肝细胞癌。肝细胞癌中AFP反映了肝癌细胞的分化状态,比血清AFP更具有特异性的肝癌标志物。
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| 关 键 词： | 肝细胞癌 乙肝表面抗原 甲胎蛋白 |
STUDY OF HBsAg AND AFP IN THE TISSUES OF HEPATOCELLULAR CARCINOMA |
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| Chang Jia-cong et al. STUDY OF HBsAg AND AFP IN THE TISSUES OF HEPATOCELLULAR CARCINOMA[J]. Chinese Journal of General Surgery, 1996, 0(1) |
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| Authors: | Chang Jia-cong et al |
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| Affiliation: | Chang Jia-cong et alDepartment of General Surgery,The First Affiliated Hospital,Anhui Medical University,Hefei 230022 |
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| Abstract: | The HBsAg and AFP in liver tissues were studied by the immunohistochemical method in 65 patients with hepatocellular carcinoma(HCC). The results showed that both HBsAg and AFP in the tissues of HCC existed mainly in the cytoplasm. This result indicated that HBV DNA might express HBsAg and made liver cell to produce AFP, and might promote the occurrance of HCC. The AFP expressed in HCC tissues might reflect the differentiation of HCC and be a more specific marker of HCC than that in serum. |
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| Keywords: | AFP Hepatocellular carcinoma. |
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