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彩超水囊引导下A型肉毒毒素注射治疗面肌痉挛的临床疗效
引用本文:洪艳,丁旭东,肖红琼,陈华先,高荣萍,汪伟,张贵斌.彩超水囊引导下A型肉毒毒素注射治疗面肌痉挛的临床疗效[J].国外医学:物理医学与康复学分册,2012,7(3).
作者姓名:洪艳  丁旭东  肖红琼  陈华先  高荣萍  汪伟  张贵斌
作者单位:洪艳 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ; 丁旭东 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ; 肖红琼 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ; 陈华先 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ; 高荣萍 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ; 汪伟 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ; 张贵斌 (湖北省医药学院附属襄阳医院神经内科,湖北,襄阳,441000) ;
摘    要:目的:探讨彩超水囊引导下肉毒毒素注射治疗面肌痉挛的疗效。方法:面肌痉挛患者96例,随机分为A、B组各48例,A组给予口服药物6个月,B组给予彩超水囊引导下局部注射A型肉毒毒素(BTX-A)。治疗前后分别采用Cohen、Acbert痉挛强度分级评估疗效,观察2组疗效、持续时间、显效率和治疗前后肌痉挛强度及变化情况。结果:A组治疗后肌痉挛强度变化无统计学差异,B组治疗后肌痉挛强度变化有显著性差异(P<0.01),且显效率高于A组(P<0.01)。结论:彩超水囊引导下BTX-A注射治疗能显著降低面肌痉挛的肌张力,且安全、简单易行。

关 键 词:彩色多普勒超声  水囊  面部肌张力障碍  A型肉毒毒素

Efficacy of Ultrasound and Water Capsule-guided Local Injection of Botulinum Toxin Type A Treatment on Patients with Facial Spasm
Abstract:Objective:To study the efficacy of ultrasound and water capsule-guided local injection of botulinum toxin type A(BTX-A) treatment on patients with facial spasm.Methods:Ninety-six cases of facial spasm were randomly divided into oral drug treatment group(A group)(48 cases) and ultrasound and water capsule-guided local injection of botulinum toxin type A treatment group(B group)(48 cases).Cohen,Acbert spasms strength grade scores in each cases with facial spasm were recorded.Therapeutic effect,duration,significant efficiency and muscle spasms strength were compared before and 6 months after treatment.Results:The muscle spasms strength showed no significant change in A group after the treatment.However,the muscle spasms strength was decreased significantly in B group after treatment(P<0.01).Conclusion:Ultrasound and water capsule-guided local injection of botulinum toxin type A treatment is a safe,effective,and simple treatment for patients with facial spasm.
Keywords:color doppler ultrasound  water capsule  facial spasm  botulinum toxin type A
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