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急性缺血性卒中静脉溶栓治疗研究新进展
引用本文:刘慧慧,姜倩梅,戴婧,刘春风. 急性缺血性卒中静脉溶栓治疗研究新进展[J]. 中国卒中杂志, 2007, 15(9): 934-941. DOI: 10.3969/j.issn.1673-5765.2020.09.003
作者姓名:刘慧慧  姜倩梅  戴婧  刘春风
作者单位:1215004.苏州大学附属第二医院神经内科;2.苏州市神经疾病临床中心
基金项目:国家自然科学基金(81701149)江苏省医学重点学科(ZDXKB2016022)苏州市临床医学中心立项项目(Szzx201503)
摘    要:
随着静脉溶栓时间窗从3 h扩展到了9 h,研究重点也从时间窗理念扩展至组织窗理念。对
于发病时间不明、醒后卒中或者一定时间内的超时间窗患者,需完善相关神经影像学检查,权衡利弊
后决定是否静脉溶栓治疗。本文重点梳理了近年来根据组织窗寻找静脉溶栓获益患者的各种不同
筛选方法及静脉溶栓的药物选择,希望能为临床提供参考。

关 键 词:静脉溶栓  时间窗  组织窗  急性缺血性卒中  
收稿时间:2020-06-30

Advances in Intravenous Thrombolysis for Acute Ischemic Stroke
LIU Hui-Hui,JIANG Qian-Mei,DAI Jing,LIU Chun-Feng. Advances in Intravenous Thrombolysis for Acute Ischemic Stroke[J]. Chinese Journal of Stroke, 2007, 15(9): 934-941. DOI: 10.3969/j.issn.1673-5765.2020.09.003
Authors:LIU Hui-Hui  JIANG Qian-Mei  DAI Jing  LIU Chun-Feng
Abstract:
As the time window of intravenous thrombolysis extended from 3 hours to 9
hours, the research focus shifted from the time window to the tissue window. For acute ischemic
stroke patients with unknown exact time of onset, wake-up stroke or beyond the 4.5-hour time
window, relevant neuroimaging examination is needed to weigh the profit and risk of intravenous
thrombolysis. This article summarized thrombolytic drugs and recent various approaches of
identifying patients eligible for intravenous thrombolysis based on the tissue window, to provide
reference for clinical practice in this field.
Keywords:Intravenous thrombolysis  Time window  Tissue window  Acute ischemic stroke  
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