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| 调节性T细胞与Th17细胞之间平衡作用的机制 | |
| 引用本文： | 武华栋,王新华,周荣斌. 调节性T细胞与Th17细胞之间平衡作用的机制[J]. 中国热带医学, 2011, 11(9): 1164-1166 |
| 作者姓名： | 武华栋 王新华 周荣斌 |
| 作者单位： | 北京军区总医院急诊科,北京,100700 |
| 摘 要： | 调节性T细胞（Treg）在维持免疫稳态和阻止自身免疫病的发生上发挥着关键的作用,这些细胞的缺失或者调节功能失调会导致免疫功能紊乱及自身免疫病的发生。因此对这些细胞有效的应用将有可能治疗自身免疫病以及阻止器官移植中的移植物排斥反应。而在维持免疫耐受的同时保证有效防御反应的关键就是Treg和Th17细胞之间的平衡。现着重介绍两种主要的Treg的类型,及其与Th17细胞间平衡机制的研究进展。 |
| 关 键 词： | 调节性T细胞 Th17细胞 |
Current research in the balance between regulatory T cells and Th17 |
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| WU Hua-dong,WANG Xin-hua,ZHOU Rong-bin. Current research in the balance between regulatory T cells and Th17[J]. China Tropical Medicine, 2011, 11(9): 1164-1166 | |
| Authors: | WU Hua-dong WANG Xin-hua ZHOU Rong-bin |
| Affiliation: | WU Hua-dong,WANG Xin-hua,ZHOU Rong-bin.(Emergency Department of Beijing Military General Hospital,Beijing 100700,P.R.China,Coprresponding uthor:ZHOU Rong-bin:E-mail:Dr_zhourongbin@sina.com) |
| Abstract: | Regulatory T cells subsets play a crucial role in the maintenance of immune homeostasis and the prevention of autoimmune disease.the lack or dysfunction of these cells may result in resistance mechanism disorders and development of many autoimmune diseases.Therefore,manipulation of these cells may provide a novel therapeutic approach to treat autoimmune diseases and prevent allograft rejection during organ transplantation.The balance of Treg and Th17 cells is thought to be critical in maintaining immune tol... |
| Keywords: | regulatory T cells Th17 cells |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |