|
|||||
|
|
| 血清SVCAM-1和PON1对老年2型糖尿病心脑血管并发症的影响 | |
| 引用本文： | 尚可,耿淑坤,易莲,孙亚威,刘冬青,郭建政. 血清SVCAM-1和PON1对老年2型糖尿病心脑血管并发症的影响[J]. 中国热带医学, 2011, 11(6): 762-763 |
| 作者姓名： | 尚可 耿淑坤 易莲 孙亚威 刘冬青 郭建政 |
| 作者单位： | 1. 河北工程大学医学院,河北,邯郸,056000 2. 邯郸市第一医院,河北,邯郸,056000 3. 邯郸市人民医院,河北,邯郸,056000 |
| 摘 要： | 目的探讨血清可溶性血管细胞粘附分子-l（SVCAM-1）水平和对氧磷酯酶1（PON，）与老年2型糖尿病心脑血管并发症的关系。方法将62例老年2型糖尿病患者分为心脑血管并发症组（32例），无心脑血管并发症组（30例）。并选取36例非糖尿病的健康者为对照组。测定老年2型糖尿病各组患者及健康老年人血清对氧磷酯酶1（PON1）、可溶性血管细胞粘附分子-1（SVCAM-1）。结果2型糖尿病心脑血管并发症组SVCAM-1高于无心脑血管并发症组和对照组，无心脑血管并发症组高于对照组；2型糖尿病心脑血管并发症组PON。低于无心脑血管并发症组和对照组，无心脑血管并发症组低于对照组。血清sVCAM-1与收缩压（SBP）、舒张压（DBP）、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白（LDL—C）显著正相关，与高密度脂蛋白（HDL—C）、PON1显著负相关。结论SVCAM-1和PON1在老年2型糖尿病心脑血管并发症的发生中起重要作用，血管内皮功能障碍可能参与其中。 |
| 关 键 词： | 可溶性血管细胞粘附分子-1 对氧磷酯酶1 2型糖尿病 心脑血管并发症 |
Impact of level of serum SVCAM-1 and PON_1 cardiovascular complications in senile type 2 diabetes mellitus patients |
|
| SHANG Ke,GENG Shu-kun,YI Lian,et al.. Impact of level of serum SVCAM-1 and PON_1 cardiovascular complications in senile type 2 diabetes mellitus patients[J]. China Tropical Medicine, 2011, 11(6): 762-763 | |
| Authors: | SHANG Ke GENG Shu-kun YI Lian et al. |
| Affiliation: | SHANG Ke,GENG Shu-kun,YI Lian,et al.(1.Hebei Engineering University Medical College,handan 056000,Hebei,P.R.China) |
| Abstract: | Aim To investigate the level of serum SVCAM-1 and PON1 on cardiovascular comp [lications in senile type 2 diabetes mellitus(T2DM)patients.Methods Sixty-two senile T2DM patients enrolled in this study were divided into non-cardiocerebral vascular complications group(n=30)and cardiocerebral vascular complications group(n=32).Thirty-six healthy individuals served as a control group.Serum SVCAM-1 and PON1 were measured.Results The SVCAM-1 levels was higher in T2DM patients with cardiocerebral vascular complicat... |
| Keywords: | Serum vascular cell adhesion molecule-1 Paraoxonase 1 type 2 diabetes mellitus Cardiocerebral Vascular Complications |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |