EBIC-Guidelines for management of severe head injury in adults期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

EBIC-Guidelines for management of severe head injury in adults

Authors:	A. I. R. Maas M. Dearden G. M. Teasdale R. Braakman F. Cohadon F. Iannotti A. Karimi F. Lapierre G. Murray J. Ohman L. Persson F. Servadei N. Stocchetti A. Unterberg

Affiliation:	(1) Department of Neurosurgery, University Hospital Rotterdam, Rotterdam, The Netherlands;(2) Anaesthetic Department, Leeds General Infirmary, Leeds, UK;(3) Department of Neurosurgery, Institute of Neurological Sciences, The Southern General Hospital, Glasgow, UK;(4) Berkel Enschot, The Netherlands;(5) Department of Neurosurgery, Hôspital Pellegrin, Bordeaux, France;(6) Department of Neurosurgery, Southhampton General Hospital, Southampton, UK;(7) Neurochirurgische Klinik, Universität zu Köln, Köln, Germany;(8) Service de Neurochirurgie, Hospital Jean Bernard, Poitiers, France;(9) Medical Statistics Unit, University of Edinburgh, Medical School, Edinburgh, UK;(10) Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland;(11) Department of Neurosurgery, Akademiska Hospital, Uppsala, Sweden;(12) Cesena Soccorso, Ospedale M. Bufalini, Cesena (FO), Italy;(13) Terapia Intensiva Neurochirurgica, Pad. Beretta Neuro/Ospedale Policlinico, Milano, Italy;(14) Department of Neurosurgery, Virchow-Klinikum, Medizinische Fakultät der Humboldt Universität zu Berlin, Berlin, Germany

Abstract:	Summary Guidelines for the management of severe head injury in adults as evolved by the European Brain Injury Consortium are presented and discussed. The importance of preventing and treating secondary insults is emphasized and the principles on which treatment is based are reviewed. Guidelines presented are of a pragmatic nature, based on consensus and expert opinion, covering the treatment from accident site to intensive care unit. Specific aspects pertaining to the conduct of clinical trials in head injury are highlighted. The adopted approach is further discussed in relation to other approaches to the development of guidelines, such as evidence based analysis.

Keywords:	Brain injury intensive care secondary insults clinical trials
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