| 乙酸局部注射治疗裸鼠移植性肝癌 |
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| 引用本文： | 闻勤生,赵永锋,贾战生,焦成松. 乙酸局部注射治疗裸鼠移植性肝癌[J]. 医学争鸣, 2001, 22(10): 929-931 |
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| 作者姓名： | 闻勤生 赵永锋 贾战生 焦成松 |
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| 作者单位： | 第四军医大学唐都医院消化内科,;第四军医大学唐都医院传染科, |
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| 摘 要： | 目的：观察局部注射乙酸对裸鼠移植性肝癌的治疗作用,为临床应用此方法治疗肝癌提供实验依据,方法：建立裸鼠移植性肝癌模型,观察治疗后肿瘤体积,光镜及电镜变化,结果：在第4次注射乙酸前,裸鼠移植瘤消失,疗效优于乙醇注射组（P＜0．01）,且无明显毒副作用,结论：乙酸可用于肝癌的局部注射治疗,有较好的疗效。
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| 关 键 词： | 肝肿瘤 乙酸 裸鼠 |
| 文章编号： | 1000-2790(2001)10-0929-03 |
| 修稿时间： | 2000-12-16 |
Treatment of transplanted hepatocellular carcinoma in nude mice with local acetic acid injection |
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| WEN Qin-Sheng,ZHAO Yong-feng,JIA Zhan-sheng,JIAO Cheng-Song. Treatment of transplanted hepatocellular carcinoma in nude mice with local acetic acid injection[J]. Negative, 2001, 22(10): 929-931 |
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| Authors: | WEN Qin-Sheng ZHAO Yong-feng JIA Zhan-sheng JIAO Cheng-Song |
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| Abstract: | AIM To observe the effects of local acetic acid injection on hepatocellular carcinoma. METHODS By establishing a model of transplanted tumor in nude mice, the changes of size and histology of tumor were observed after injecting acetic acid, ethanol and saline. RESULTS Transplanted hepatocellular carcinoma disappeared before the fourth injecting acetic acid. The treatment effect of acetic acid injection on hepatocellular carcinoma was superior to ethanol injection. There were no significant toxic and side effects after acetic acid injection. CONCLUSION Acetic acid can be used for local injection therapy on hepatocellular carcinoma. |
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| Keywords: | liver neoplasms acetic acid nude mice |
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