甲状腺球蛋白抗体、甲状腺微粒体抗体不同条件下在血清中的稳定性

目的探讨甲状腺球蛋白抗体（TGAb）和甲状腺微粒体抗体（TMAb）不同条件下在血清中的稳定性。方法用放射免疫法测定放置室温、4℃冰箱、冰冻条件下,不同时间段血清样本中的TGAb与TMAb的活性。结果3种条件在储存2d以后的结果差异无统计学意义;储存4d后,室温条件下样品的TGAB与TMAb失活;储存6d后,4℃冰箱条件下样品的TGAb与TMAb失活;储存29d后,冰冻条件下样品的TGAb与TMAb失活。结论使用4℃冰箱保存4d内的血样进一步作甲状腺抗体的检测,可以保证其准确性且又不影响日常临床工作。

Thyrogiobulin antibody (TGAb), thyroid microsomal antibodies (TMAb) under different conditions in the sta-bility of the serum

Objective To investigate the thyroglobulin antibody (TGAb) and thyroid microsomal anti-bodies (TMAb) under different conditions in the serum Stability. Methods Measured by radioimmunoassay place at room temperature, 4℃ refrigerator, ice conditions, the different time periods in serum samples of TGAb and TMAb activity. Results Three conditions in the storage Two days later the results of no signifi-cant difference; stored 4 days at room temperature samples TGAb and TMAb inactivation; storage 6 days, 4 ℃ refrigerator under the conditions of the samples TGAb and TMAb inactivation; store 29 days later, the frozen samples under the conditions of TGAb and TMAb inactivation. Conclusion 4 ℃ refrigerator used to preserve blood samples for further screening for thyroid antibodies, the most suitable for day-to-day clinical work.