| 术前左心功能不全是心脏手术后发生急性肾损伤的独立危险因素 |
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| 引用本文： | 戴慧莉,车妙琳,郦忆,薛松,谢波,朱铭力,钱家麒,倪兆慧,严玉澄. 术前左心功能不全是心脏手术后发生急性肾损伤的独立危险因素[J]. 上海医学, 2009, 32(8) |
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| 作者姓名： | 戴慧莉 车妙琳 郦忆 薛松 谢波 朱铭力 钱家麒 倪兆慧 严玉澄 |
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| 作者单位： | 上海交通大学医学院附属仁济医院肾脏科,200127;上海交通大学医学院附属仁济医院心胸外科,200127 |
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| 基金项目： | 上海市医学发展基金重点研究课题资助项目 |
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| 摘 要： | 目的 评价心脏手术患者术前心功能对术后并发急性肾损伤(AKI)的影响.方法 回顾性分析2004年1月1日-2007年6月30日在上海交通大学医学院附属仁济医院行心脏手术的所有住院患者的资料,采用AKI网络(AKIN)推荐的AKI定义统计心脏手术后AKI的发生率,对患者术前的心功能进行评估,并分析其他可能造成术后AKI的危险因素.结果 1 056例患者中,术后发生AKI 328例,发生率为31.1%.AKI组的院内病死率为11.6%(38/328),显著高于非AKI组的0.7%(5/728,P＜0.01).多因素Logistic回归分析显示,在校正年龄、术前高尿酸血症、冠状动脉旁路移植联合瓣膜手术、手术时间、术后循环血容量不足等因素后,术前左心功能不全仍是心脏手术后发生AKI的独立危险因素(OR=2.53,95%CI为1.24～5.13,P=0.01).结论 术前左心功能不全是心脏手术后发生AKI的独立危险因素.
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| 关 键 词： | 急性肾损伤 心脏手术 术前心功能 危险因素 |
Pre-operative cardiac dysfunction is associated with acute kidney injury following cardiac surgery |
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| DAI Huili,CHE Miaolin,LI Yi,XUE Song,XIE BO,ZHU Mingli,QIAN Jiaqi,NI Zhaohui,YAN Yucheng. Pre-operative cardiac dysfunction is associated with acute kidney injury following cardiac surgery[J]. Shanghai Medical Journal, 2009, 32(8) |
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| Authors: | DAI Huili CHE Miaolin LI Yi XUE Song XIE BO ZHU Mingli QIAN Jiaqi NI Zhaohui YAN Yucheng |
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| Affiliation: | DAI Huili,CHE Miaolin,LI Yi,XUE Song,XIE Bo,ZHU Mingli,QIAN Jiaqi,NI Zhaohui,YAN Yucheng.Department of Nephrology,Renji Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200127,China |
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| Abstract: | Objective To assess the influence of the pre-operative cardiac function on the incidence of acute kidney injury(AKI)following cardiac surgeries.Methods We retrospectively analyzed the patients who underwent open heart surgery in Renji Hospital,Shanghai Jiaotong University School of Medicine from Jan.1st 2004 to Jun.30th 2007.Univariate and multivariate analyses were used to evaluate possible pre-,intra-,and post-operation parameters associated with AKI using AKI Network(AKIN).Results Of the 1056 patients,32... |
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| Keywords: | Acute kidney injury Cardiac surgery Pre-operative cardiac function Risk factors |
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