难愈糖尿病足患者感染病原菌分布及感染特征

糖尿病足部慢性难愈创面造成了较高的致残率。40%～80%的糖尿病足溃疡合并感染。慢性难愈创面感染的主要特征是混合感染、异位感染、多重耐药菌感染。随着对难愈创面发生机制和创面愈合过程的深入了解以及各种有效地生长因子转入技术、医用新材料和创面治疗新技术如负压创面治疗技术的应用和成熟,难愈创面愈合有望成为现实。现对糖尿病足难愈溃疡患者感染病原菌分布、感染特征、发生机制及目前应用的治疗新技术作一综述。

The Pathogen Distribution and the Infection Characteristic of Refractory Diabetic Foot Ulcers with Infection

The chronic refractory diabetic ulcer induced high mutilation rate. The prevalence of diabetic foot ulcer infection ranges from 40% to 80%. The mainfeatures of chronic refractory ulcer infection were mixed infection, dystopia infection and muhidrug resistant infection. With the mechanism of refractory wound and the wound healing process of in-depth understanding of, and a variety of growth factors and effective delivery technology,medical treatment of new materials and new technologies,such as negative pressure wound wound therapy the applicataion of and mature,and refractory wound healing is expected to become a reality.