雷贝拉唑与泮托拉唑治疗十二指肠溃疡的对照评价

目的:评价雷贝拉唑和泮托拉唑治疗十二指肠溃疡的临床疗效及其安全性.方法:将Hp检测阳性,内镜检查为活动期十二指肠溃疡的患者分为治疗组(雷贝拉唑三联疗法);对照组(泮托拉唑三联疗法);服药1周.两组继续使用雷贝拉唑或泮托拉唑1周为1疗程.结束后第28天复查内镜并检测Hp.结果:内镜检查结果和Hp检测结果及不良反应两组对比无统计学差异(P＞0.05).结论:雷贝拉唑和泮托拉唑对十二指肠溃疡具有良好的治疗作用和安全性.

A Comparative Evaluation of Rebeprazole and Pantoprazole in Treating Duodenal Ulcer

Objective: To evaluate the efficacy and safety of rebeprazole and pantoprazole in treating duodenal ulceration. Method : The patients suffering duodenal ulcer who were Hp-test positive and in active period examined by endoscopy were divided into two groups. Patients in therapy group were treated with rebeprazole-based triple therapy and the control group was treated with pantoprazole-based triple therapy for one week. Then they were treated with rebeprazole or pantoprazole continuously for one week respectively. Hp test and endoscopy examination were implemented 28 days again after the therapy was finished. Result: There were no statistical differences in side effects, Hp-test results and endoscopy examination results between two groups. Conclusion: Rebeprazole and Pantoprazole are effective and safe in treating duodenal ulcer.